Results 41 to 50 of about 8,402,764 (256)

Factors impacting long-term care and retirement home populations’ participation in immunity research: a qualitative study using the framework method

open access: yesBMC Geriatrics
Background The COVID-19 pandemic had a severe impact on Long-Term Care Homes (LTCH) and Retirement Homes (RH) in Canada. Urgent research was required to understand characteristics of COVID-19 transmission and immunity among this at-risk population, yet ...
Christine Fahim   +6 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Towards a taxonomy of behavior change techniques for promoting shared decision making

open access: yesImplementation Science, 2020
Background There is little information about the functions and behavior change techniques (BCTs) needed to implement shared decision making (SDM) in clinical practice.
Titilayo Tatiana Agbadjé   +4 more
doaj   +1 more source

Theory-based approach to developing an implementation plan to support the adoption of a patient decision aid for Down syndrome prenatal screening

open access: yesImplementation Science, 2021
Background Our team has developed a decision aid to help pregnant women and their partners make informed decisions about Down syndrome prenatal screening. However, the decision aid is not yet widely available in Quebec’s prenatal care pathways. Objective
Titilayo Tatiana Agbadjé   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Comparative effectiveness and safety of pharmacological and non-pharmacological interventions for insomnia: an overview of reviews

open access: yesSystematic Reviews, 2019
Background This review aimed to assess the existing evidence regarding the clinical effectiveness and safety of pharmacological and non-pharmacological interventions in adults with insomnia and identify where research or policy development is needed ...
Patricia Rios   +10 more
doaj   +1 more source

Comparative efficacy and complications of long-acting and intermediate-acting insulin regimens for adults with type 1 diabetes: an individual patient data network meta-analysis

open access: yesBMJ Open, 2022
Objective To examine the comparative efficacy and complications of long-acting and intermediate-acting insulin for different patient characteristics for type 1 diabetes mellitus (T1DM).Design Systematic review and individual patient data (IPD) network ...
Dimitris Mavridis   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Use of implementation science methods to design Wellness Hub, a responsive program to address long-term care and retirement homes’ challenges during the COVID-19 pandemic

open access: yesBMC Health Services Research
Background Long-term care and retirement homes (LTCH/RH) faced systemic challenges that were exacerbated by the COVID-19 pandemic. Homes faced three major challenges over the course of the pandemic: implementing infection prevention and control (IPAC ...
Christine Fahim   +15 more
doaj   +1 more source

Characterizing Canadian funded partnered health research projects between 2011 and 2019: a retrospective analysis

open access: yesHealth Research Policy and Systems, 2023
Background and Aims Involving research users in collaborative research approaches may increase the relevance and utility of research findings. Our primary objectives were to (i) identify and describe characteristics of Canadian federally and provincially
Kathryn M. Sibley   +9 more
doaj   +1 more source

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