Results 71 to 80 of about 497,473 (309)
Knowledge Transfer-Enhanced Contrastive Learning for Long-Tailed User Recommendation
IEEE AccessIn recommendation systems, Graph Convolutional Networks (GCNs) have shown superior performance by exploiting high-order relationships. However, generating accurate recommendations for long-tailed users with sparse interactions in large-scale scenarios ...
Xiangling Lei, Hongwei Zhang
doaj +1 more source
Knowledge push based on design flow and user capacity model
MATEC Web of Conferences, 2017 The knowledge demand of the designer is determined by the knowledge structure of the knowledge user and knowledge usage scenario. Therefore, this paper proposes a knowledge push method based on design activities workflow model and user capability model ...
Jiang Hao, Yin Pu, Guo Lin, Wang Yibo
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
From ‘other’ to involved: User involvement in research: An emerging paradigm [PDF]
, 2013 This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ 2013 The Author(s). This is an Open Access article.
Beresford, P
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Knowledge user survey and Delphi process to inform development of a new risk of bias tool to assess systematic reviews with network meta-analysis (RoB NMA tool) [PDF]
BMJ Evid Based Med, 2023 Lunny C +20 more
europepmc +2 more sources
USER MOTIVATION AND KNOWLEDGE SHARING IN IDEA CROWDSOURCING [PDF]
International Journal of Innovation Management, 2014 We investigate how the propensity to trust, intrinsic motivation, and extrinsic motivation drive the intentions of individuals to share knowledge in idea crowdsourcing. Building on motivation theories and Uses & Gratifications (U&G) approach, we conducted a web-based survey within IdeasProject, an open innovation and brainstorming community ...
MIIA KOSONEN +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source