Results 41 to 50 of about 2,462,838 (342)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

First reliable record of Liparis punctulatus (Scorpaeniformes: Liparidae) in Korea

open access: yesFisheries and Aquatic Sciences, 2021
A single specimen of Liparis punctulatus (30.9 mm standard length) belonging to the family Liparidae, was collected in the waters off Busan on 4 August, 2016.
Gyeong Hyun Park, Jin-Koo Kim
doaj   +1 more source

The Korean system of innovation and the semiconductor industry [PDF]

open access: yes, 1996
노트 : This paper is written as part of the Science Policy Research Unit/Sussex European Institute-joint project ‘‘Innovation Dynamics of Pacific Asia: Implications for Europe’’
Kim, S. Ran
core  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Characteristics and Survival of Korean Patients With Colorectal Cancer Based on Data From the Korea Central Cancer Registry Data [PDF]

open access: yesAnnals of Coloproctology, 2018
Purpose The incidence of colorectal cancer (CRC) in Korea has increased remarkably during the past few decades. The present study investigated the characteristics and survival of patients with CRC in Korea as a function of time, tumor distribution, stage,
Hyuk Hur   +4 more
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Ključni momenti jugoslavenske i hrvatske diplomacije od 1941. do 1956.

open access: yesMeđunarodne Studije, 2015
Autor nastoji dati uvid u ključne momente jugoslavenske i hrvatske diplomacije od napada sila Osovine na Kraljevinu Jugoslaviju u travnju 1941. do sovjetske intervencije u Mađarskoj u studenom 1956. godine.
Bruno Korea Gajski
doaj  

Eun Kyeong Cho Assistant Professor of Education, COLA, travels to South Korea [PDF]

open access: yes, 2011
Professor Cho traveled to South Korea in summer 2011 to make a presentation at an international seminar and to meet colleagues to continue an on going collaboration with South Korean researchers at the Korea Institute of Child Care and Education (KICCE)
Cho, Eun Kyeong
core   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

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