Results 51 to 60 of about 1,238,441 (311)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims To investigate the efficacy and safety of tocilizumab (TCZ) humanized anti-interleukin-6 receptor monoclonal antibody, in Korean patients with active rheumatoid arthritis (RA) refractory to conventional disease modifying anti-rheumatic ...
Han Joo Baek   +11 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Analysis of the relationship between sugar intake and cancer prevalence: a cross-sectional study using the 8th Korea National Health and Nutrition Examination Survey [PDF]

open access: yesKorean Journal of Community Nutrition
Objectives This study aimed to analyze the association between sugar intake and cancer risk among Korean adults aged 19 years and older. Methods A total of 13,016 adults aged 19 years and older who participated in the 8th Korea National Health and ...
Hye-Ryun Kim, Soo-Kyung Lee
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Contemporary cultures and their relationship to adolescent behavior (Korean culture) as a model

open access: yesمجلة فنون البصرة, 2023
Going into any aspect of adolescence is one of the important basics for evaluating society, this is due to the importance of this age stage that determines building the personality of a normal individual and establishing him in a positive way for his ...
Zahra Hadi Kazem
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Simple and effective neural coreference resolution for Korean language

open access: yesETRI Journal, 2021
We propose an end‐to‐end neural coreference resolution for the Korean language that uses an attention mechanism to point to the same entity. Because Korean is a head‐final language, we focused on a method that uses a pointer network based on the head ...
Cheoneum Park   +4 more
doaj   +1 more source

Neck Circumference as a Predictor of Insulin Resistance in People with Non-alcoholic Fatty Liver Disease

open access: yesJournal of Obesity & Metabolic Syndrome, 2023
Background : Insulin resistance is common in individuals with non-alcoholic fatty liver disease (NAFLD). Because insulin resistance is a predictive factor for advanced liver diseases in people with NAFLD, efforts have been made to predict it through ...
Da-Hye Son, Jee Hye Han, Jun-Hyuk Lee
doaj   +1 more source

K-Drama dan Penyebaran Korean Wave di Indonesia

open access: yesProTVF, 2019
Korean wave is a term given to the spread of Korean popular culture through entertainment products such as drama, music, and fashion. The existence of the Korean wave in Indonesia has become an interesting phenomenon to study.
I. P. Putri   +2 more
semanticscholar   +1 more source

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