Results 51 to 60 of about 4,692,983 (163)

Safety and tolerability of Korean Red Ginseng in healthy adults: a multicenter, double-blind, randomized, placebo-controlled trial

, 2018
Background: Korean Red Ginseng (KRG) has been used in Asia for its various biological effects, but no studies have investigated the safety of its long-term intake. Therefore, the present study evaluated the safety of KRG intake for 24 weeks. Methods: We
강희철
core   +1 more source

The anti-platelet activity of panaxadiol fraction and panaxatriol fraction of Korean Red Ginseng in vitro and ex vivo

Journal of Ginseng Research, 2023
Background: The anti-platelet activity of the saponin fraction of Korean Red Ginseng has been widely studied. The saponin fraction consists of the panaxadiol fraction (PDF) and panaxatriol fraction (PTF); however, their anti-platelet activity is yet to ...
Yuan Yee Lee, Yein Oh, Min-Soo Seo, Min-Goo Seo, Jee Eun Han, Kyoo-Tae Kim, Jin-Kyu Park, Sung Dae Kim, Sang-Joon Park, Dongmi Kwak, Man Hee Rhee   +10 more
doaj   +1 more source

Protective effects of extracellular vesicle‐like nanoparticles derived from Cannabis sativa adventitious roots against UVB‐induced damage in human keratinocytes

International Journal of Cosmetic Science, EarlyView.
Cannabis sativa root‐derived extracellular vesicle‐like nanoparticles (CA‐NPs) were isolated from adventitious root cultures and subjected to physicochemical characterization. Upon UVB exposure, keratinocytes exhibited increased ROS generation, apoptosis and MAPK activation, leading to oxidative stress and skin damage.
Dong Ho Bak, Su Hyun Park, Young Bae Ryu, Cha Young Kim, Jae Cheol Jeong, Woo Sik Kim   +5 more
wiley   +1 more source

Protective effect of Korean Red Ginseng on cisplatin ototoxicity: Is it effective enough?

, 2016
OBJECTIVE: The aim of our study was to investigate the effects Korean Red Ginseng (KRG) on cisplatin (CDDP) ototoxicity in vivo and in ...
Safiye Aktas, Bulent Serbetcioglu, Kırkım, G., Kolatan, E., Olgun, Y., GÜNERİ, ENİS ALPİN, Ercetin, Pinar, Kizmazoglu, Deniz Cakir, Şerbetçioğlu, B., Olgun, Aybuke, Aktaş, S., Muge Kiray, Deniz Cakir Kizmazoglu, Serbetcioglu, Bulent, Yılmaz, O., Altun, Z., Güneri, E.A., Kiray, M., Ellidokuz, H., Gunay Kirkim, Osman Yilmaz, Yuksel Olgun, Candan Ozogul, Bağrıyanık, A., Yilmaz, Osman, Kızmazoğlu, D.Ç., Zekiye Altun, ELLİDOKUZ, HÜLYA, Özoğul, C., Enis Alpin Guneri, KIRKIM, GÜNAY, Altun, Zekiye, Olgun, A., Kolatan, Efsun, Pinar Ercetin, Erçetin, P., Alper Bagriyanik, KİRAY, MÜGE, Hulya Ellidokuz, Aybuke Olgun, OLGUN, YÜKSEL, Ozogul, Candan, AKTAŞ, SAFİYE, Efsun Kolatan, Bagriyanik, Alper   +44 more
core   +2 more sources

Protective effect of Korean Red Ginseng against glucocorticoid-induced osteoporosis in vitro and in vivo

Journal of Ginseng Research, 2015
Background: Glucocorticoids (GCs) are commonly used in many chemotherapeutic protocols and play an important role in the normal regulation of bone remodeling.
Jinhee Kim, Hyejin Lee, Ki Sung Kang, Kwang-Hoon Chun, Gwi Seo Hwang   +4 more
doaj   +1 more source

Long-term evaluation of safety and biological effects of Korean Red Ginseng (Panax Ginseng): a long-term in vivo study

BMC Complementary Medicine and Therapies, 2022
Background Although Korean Red Ginseng (KRG) is safe, this finding was only evaluated in 3-mo-long studies. Its safety was verified through a 6-mo KRG administration clinical study, but long-term studies beyond 6 mo are insufficient.
Soo Kyung Park, Sung-Won Kim, Hwi Won Seo, Sun Hee Hyun, Jong-Su Kyung, Soo-Hyun Youn, Seung Ho So, Gyo In, Chae-Kyu Park, Eugene C. Yi, Chang-Kyun Han, Yong Yook Lee   +11 more
doaj   +1 more source

Newly identified maltol derivatives in Korean Red Ginseng and their biological influence as antioxidant and anti-inflammatory agents

Journal of Ginseng Research, 2023
Background: Korean Red Ginseng is a major source of bioactive substances such as ginsenosides. Efficacy of red ginseng extract (RGE), which contains not only saponins but also various non-saponins, has long been studied.
Jeong Hun Cho, Myoung Chong Song, Yonghee Lee, Seung-Taek Noh, Dae-Ok Kim, Chan-Su Rha   +5 more
doaj   +1 more source

The Effect of Microbiome‐Modulating Therapeutics on Anthropometric and Hemodynamic Biomarkers in Metabolic Syndrome: A Systematic Review, Meta‐Analysis, and Meta‐Regression of Clinical Trials

Obesity Reviews, EarlyView.
ABSTRACT Background Metabolic syndrome (MetS) is a prevalent cardiometabolic disorder characterized by central obesity, insulin resistance, dyslipidemia, and hypertension. Microbiome‐targeted therapies with probiotics, prebiotics, and synbiotics may improve outcomes by modulating metabolism, inflammation, and blood pressure.
Pradipta Paul, Iman Dajani, Ridhima Kaul, Ali Chaari   +3 more
wiley   +1 more source

Multitarget effects of Korean Red Ginseng in animal model of Parkinson's disease: antiapoptosis, antioxidant, antiinflammation, and maintenance of blood–brain barrier integrity

Journal of Ginseng Research, 2018
Background: Ginsenosides are the main ingredients of Korean Red Ginseng. They have extensively been studied for their beneficial value in neurodegenerative diseases such as Parkinson's disease (PD).
Jong Hee Choi, Minhee Jang, Seung-Yeol Nah, Seikwan Oh, Ik-Hyun Cho   +4 more
doaj   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source