Results 261 to 270 of about 260,030 (390)

The KRAS-G12D mutation drives venous thromboembolism (VTE) and colorectal cancer progression via MAPK/ERK signaling. [PDF]

Transl Oncol
Mao J, Ming X, Wang M, Du Y, Shen Y, Li D, Zhu Z, Li X, Li J.   +8 more
europepmc   +1 more source

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer.

Journal of Clinical Oncology, 2008
R. Amado, M. Wolf, M. Peeters, E. Van Cutsem, S. Siena, Daniel J. Freeman, T. Juan, R. Sikorski, S. Suggs, R. Radinsky, S. Patterson, David D Chang   +11 more
semanticscholar   +1 more source

Impact of Baseline Nutritional Status, Psychological Health, Fatigue, and Insomnia on Outcomes of Immune Checkpoint Inhibitors in Advanced Non‐Small Cell Lung Cancer: A Retrospective Cohort Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the impact of pretreatment nutritional status, psychological health, fatigue, and insomnia on outcomes of immune checkpoint inhibitors (ICIs) monotherapy in patients with advanced non‐small cell lung cancer (NSCLC). A total of 80 patients with stage IV NSCLC were enrolled.
Yu‐Xuan Zhu, Yuan‐Yuan Zhang, Xiu‐Juan Jiang   +2 more
wiley   +1 more source

KRAS Copy Number Gain in Cell-Free DNA Analysis-Based Liquid Biopsy of Plasma and Bile in Patients with Various Pancreatic Neoplasms. [PDF]

Int J Mol Sci
Jain M, Atayan D, Rakhmatullin T, Dakhtler T, Inokenteva V, Popov P, Farmanov A, Viborniy M, Gontareva I, Samokhodskaya L, Egorov V.   +10 more
europepmc   +1 more source

Sarcospan (Kras oncogene-associated gene) (SSPN) [PDF]

, 2008

openalex   +1 more source

Primary Head and Neck Histiocytic Sarcoma of the Oropharyngeal Posterolateral Wall: A Case Report

The Laryngoscope, EarlyView.
Histiocytic sarcoma (HS) is a rare and aggressive malignancy, particularly uncommon in the head and neck region. This report describes the case of a 67‐year‐old male with HS originating from the oropharyngeal posterolateral wall, treated successfully with transoral CO2 laser excision and adjuvant proton radiotherapy.
Michael Dalè, Giulia Gabella, Pietro Benzi, Valentina Campagnari, Marta De Vecchi, Monica Feltri, Marta Filauro, Giorgio Peretti, Giampiero Parrinello   +8 more
wiley   +1 more source

Editorial: RAS inhibitor therapy of cancer. [PDF]

Front Oncol
Buchsbaum DJ, Nassar NN, Piazza GA.
europepmc   +1 more source

Chemical genetic screening of KRAS-based synthetic lethal inhibitors for pancreatic cancer [PDF]

, 2009
Zhenyu Ji, Fang Mei, Pedro L Lory, Scott R. Gilbertson, Yijun Chen, Xiaodong Cheng   +5 more
openalex   +1 more source

Evaluation of HER2 Targeted Poly(Ethylene Glycol)‐Poly(L‐histidine) Copolymer Micelles in Breast Cancer Models

Macromolecular Bioscience, EarlyView.
This study reports on the in vitro, ex vivo, and in vivo evaluation of HER2 targeted biodegradable micelle variants, conjugated with trastuzumab, with or without the drug doxorubicin or the dye rhodamine B. Findings indicate enhanced cellular association and efficacy of trastuzumab‐conjugated micelles in HER2 positive breast cancer models, showing ...
Remya Valsala Kumari, Abhilash D. Pandya, Solveig J. Pettersen, Audun Kvalvaag, Anne Grethe Myrann, Razvan Ghiarasim, Alexandru Rotaru, Mihail‐Gabriel Dimofte, Tore Skotland, Kirsten Sandvig, Gunhild Mari Mælandsmo, Tore‐Geir Iversen   +11 more
wiley   +1 more source

An in vitro BRAF activation assay elucidates molecular mechanisms driving disassembly of the autoinhibited BRAF state. [PDF]

Proc Natl Acad Sci U S A
Ritt DA, Durrant DE, Drew MR, Sandin SI, Martinez Fiesco JA, Zhang X, Aydin F, Carpenter TS, Scheidemantle GM, D'Ippolito RA, Sohn AL, DeHart CJ, Shrestha R, Snead K, Hull J, Tempkin JOB, Yang Y, Lightstone FC, Streitz FH, Zhang P, Turbyville TJ, Stephen AG, Esposito D, Ingólfsson HI, Nissley DV, Morrison DK.   +25 more
europepmc   +1 more source