Results 311 to 320 of about 260,030 (390)

Novel paradigms in KRAS targeting: Unveiling strategies to combat drug resistance. [PDF]

Chin Med J (Engl)
Luo X, Zhou F, Tang Y, Liu X, Xiao R, Gu M, Bai J, Jiang D, Yang G, You L, Zhao Y.   +10 more
europepmc   +1 more source

Exome‐wide molecular insights from blood and urine liquid biopsies in genitourinary cancers

UroPrecision, EarlyView.
Abstract Background Liquid biopsy has emerged as a non‐invasive method for real‐time cancer monitoring especially in genitourinary (GU) oncology. Most current studies utilize a panel‐based molecular profiling ranging from 50–600 genes; however, a comprehensive exome‐wide profiling of real‐world patient samples has been lacking. Methods Over 2000 liquid
Eric Jia, Tiantian Zheng, Yong Huang, Pan Du   +3 more
wiley   +1 more source

Comprehensive analysis of <i>KRAS</i> aberrations in pan-cancer, with a focus on prognostic and therapeutic implications. [PDF]

Ther Adv Med Oncol
Jung J, Hong JY, Park SH, Park JO, Park YS, Lim HY, Kang WK, Lee J, Ha SY, Ahn S, Lim SH, Kim ST.   +11 more
europepmc   +1 more source

Brain metastasis in non‐small cell lung cancer: High‐risk factors and predictive models

VIEW, EarlyView.
Artificial intelligence (AI) can integrate of data to predict brain metastases (BM) in non‐small cell lung cancer (NSCLC). AI algorithms are employed to analyze these multifaceted datasets, enabling the identification of complex patterns and correlations that may not be apparent through traditional analytical methods.
Chen Gong, Ben Zhao, Shuangshuang Mao, Qingxu Liu, Yuanyuan Zhao, Yiwen Liu, Yao Luo, Qianxia Li   +7 more
wiley   +1 more source

Gastric Foveolar-Type Hyperplastic Polyp of the Duodenum With <i>GNAS</i> and <i>KRAS</i> Mutations: A Potential Precursor to Neoplasia. [PDF]

DEN Open
Yamazaki K, Kushima R, Ozawa N, Koizumi H, Hayashi S, Soga A, Yamashita K, Shimizu S, Shimizu M.   +8 more
europepmc   +1 more source

KRAS mutational status assessment in patients with metastatic colorectal cancer: are the clinical implications so clear?

, 2009
Mohamed Hebbar, Peggy Fournier, Onofrio Romano   +2 more
openalex   +1 more source

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.

New England Journal of Medicine, 2016
E. Tran, P. Robbins, Yong-Chen Lu, Todd D Prickett, J. Gartner, Li Jia, A. Pasetto, Zhili Zheng, Satyajit Ray, E. Groh, Isaac R. Kriley, S. Rosenberg   +11 more
semanticscholar   +1 more source

Inhibition of MEK, a canonical KRAS pathway effector in KRAS mutant NSCLC

Translational Lung Cancer Research, 2018
Niki Karachaliou, Masaoki Ito, Carles Codony-Servat, Rafael Rosell   +3 more
openaire   +3 more sources

Microfluidic single‐cell technologies for immunotherapeutic target discovery: From design concepts to preclinical applications

VIEW, EarlyView.
Immunotherapy leverages the immune system to treat cancer and autoimmune diseases but is hindered by cellular heterogeneity in tissues and immune landscapes. Single‐cell technologies, particularly microfluidic‐enabled omics, revolutionize disease understanding by resolving this complexity at unprecedented resolution.
Haopu Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Diagnostic and prognostic potential of microRNA profiles in endometrioid endometrial cancer. [PDF]

Sci Rep
Soykan Y, Yar Saglam AS, Inan MA, Ugras Dikmen A, Erdem Ö, Onan MA.   +5 more
europepmc   +1 more source