Results 131 to 140 of about 47,532 (349)

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

open access: yesAdvanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng   +40 more
wiley   +1 more source

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee   +13 more
wiley   +1 more source

MORPHOPHONOLOGICAL INTERFERENCE IN MINANGKABAU’S LANGUAGE [PDF]

open access: yes, 2017
This study analyzes entitle of: “Morphophonological Interference in Minangkabau’s Language”, which focuses on morpheme and phonetic. This study aims to find the forms of word structure and vocal along with the changing of interference between ...
Mahdi, Sutiono, Mayuni, Mayuni
core  

Test beam studies of the TRD prototype filled with different gas mixtures based on Xe, Kr, and Ar

open access: yes, 2016
Towards the end of LHC Run1, gas leaks were observed in some parts of the Transition Radiation Tracker (TRT) of ATLAS. Due to these leaks, primary Xenon based gas mixture was replaced with Argon based mixture in various parts.
Boldyrev, A. S.   +16 more
core   +1 more source

PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu   +10 more
wiley   +1 more source

THE LANGUAGE USED BY INDONESIAN LOCAL GUIDES IN GOOGLE MAPS REVIEWS [PDF]

open access: yes, 2017
Google Maps is web-mapping service developed by Google. It provides a satellite imagery, street maps, street 360°-views, Google traffic (real-time conditions), and route-planning. One of many Google Maps features is it allows the users to give a rating,
Lestari , Titin
core  

Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation

open access: yesAdvanced Science, EarlyView.
A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba   +11 more
wiley   +1 more source

MAKING MEANING USING SYSTEMIC FUNCTIONAL LINGUISTICS AND VISUAL GRAMMAR ANALYSIS: COMPARISON OF SOURCE TEXT AND TARGET TEXT REFLECTED IN THE MAIN CHARACTER OF GRAPHIC NOVEL V FOR VENDETTA [PDF]

open access: yes, 2017
This research presents a project designed to investigate a systemic way of analyzing metafunctions’ shifts between source texts and target texts using systemic functional linguistic (SFL) collaborated with visual grammar (VS; systemic functional ...
Nababan, Nababan   +2 more
core  

ZnO Quantum Dots@CsPbBr3 Poly‐Heterocrystalline Film Enables High‐Performance Floating‐Gate Transistor Arrays for Edge Computing

open access: yesAdvanced Science, EarlyView.
The ZnO QDs@CsPbBr3 poly‐heterocrystalline film, featuring a semi‐coherent interface, delivers high electrical conductivity and excellent photoelectric properties. Functioning as a floating gate in photosensitive transistors, it enables high hole storage at 1 V and achieves a conductivity ratio of ≈3.57×105.
Jiajun Xu   +9 more
wiley   +1 more source

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