Results 61 to 70 of about 7,483 (251)

Intrinsic backgrounds from Rn and Kr in the XENON100 experiment

open access: yesEuropean Physical Journal C: Particles and Fields, 2018
In this paper, we describe the XENON100 data analyses used to assess the target-intrinsic background sources radon ( ), thoron ( ) and krypton ( ). We detail the event selections of high-energy alpha particles and decay-specific delayed coincidences.
E. Aprile   +118 more
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

open access: yesAdvanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee   +11 more
wiley   +1 more source

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

open access: yesAdvanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha   +13 more
wiley   +1 more source

Krypton [PDF]

open access: yes, 2017
Jacob W. Leachman   +3 more
  +5 more sources

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

open access: yesAdvanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia   +4 more
wiley   +1 more source

Spectroscopic studies on the enhanced radiation with high Z rare gas seeding for mitigating divertor heat loads in LHD plasmas

open access: yesNuclear Materials and Energy, 2019
We have measured extreme ultraviolet (EUV) and soft X-ray emission spectra of krypton (Kr) ions in the Large Helical Device (LHD) plasmas with Kr gas seeding intended for mitigating divertor heat loads.
C. Suzuki   +6 more
doaj   +1 more source

Water‐Soluble Luminescent Trityl Radical for Fluorescence/Magnetic Resonance Dual‐Modal Imaging Probe

open access: yesAdvanced Science, EarlyView.
Stable water‐soluble luminescent tris(2,4,6‐trichlorophenyl)methyl (TTM) radicals, TTM‐trisTP3B and TTM‐trisTP9B, were designed and successfully synthesized. They exhibited deep‐red emissions and high photostability in water. TTM‐trisTP3B exhibited dual functionality as a fluorescence imaging (FI) probe and a magnetic resonance imaging (MRI) contrast ...
Kosuke Anraku   +6 more
wiley   +1 more source

The Beneficial Effects of Krypton Inhalation Following Traumatic Brain Injury in Rats

open access: yesОбщая реаниматология
Traumatic brain injury (TBI) remains one of the leading causes of disability, and current approaches to neuroprotection have limited efficacy. The inert gas krypton is considered a promising neuroprotective agent; however, data on its effects in TBI and ...
V. V. Antonova   +6 more
doaj   +1 more source

Janus Reactivity of a Mononuclear Non‐Heme Iron(III)‐Peroxo Complex Toward Indole Oxidation

open access: yesAngewandte Chemie, EarlyView.
The iron(III)‐peroxo complex [FeIII(O2)(12‐TMC)]+ exhibits bifurcating pathways in indole oxidation. N─H indoles undergo N─H H‐atom abstraction, supported by a KIE of 5.2 for N─H/N–D 2,3‐dimethylindoles, whereas N‐methylindoles react via electrophilic addition of the iron‐peroxo group to the C2–C3 double bond of the indole ring, forming iron ...
Wenjuan Zhu   +4 more
wiley   +2 more sources

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