Results 71 to 80 of about 7,483 (251)

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

Advanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng, Jaegeon Joo, Yu Meng Li, Cheng Ji Li, Ali Taghizadeh, Seung Jae Shin, Buuvee Bayarkhangai, Tae‐Woo Ha, Sak Lee, Jaewoo Chung, Bo‐Eun Yoon, Hye Sung Kim, Inkyung Jung, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +15 more
wiley   +1 more source

Advanced laboratory for testing plasma thrusters and Hall thruster measurement campaign

Nukleonika, 2016
Plasma engines are used for space propulsion as an alternative to chemical thrusters. Due to the high exhaust velocity of the propellant, they are more efficient for long-distance interplanetary space missions than their conventional counterparts.
Szelecka Agnieszka
doaj   +1 more source

The triple point of krypton

AIP Conference Proceedings, 2013
Phase transitions of pure substances provide the key reference temperatures, otherwise known as "defining fixed points", of the International Temperature Scale. At temperatures below the triple point of mercury (234.3156 K), the substances involved are gases at room temperature and include the triple points of hydrogen (13.8033 K), neon (24.5561 K ...
openaire   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

Angewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley, Michael Rust, Moritz Wagner, Ida R. Hipfinger, Paul J. N. Böhm, Cora L. Dieterich, Christopher M. Field, Michael J. Page, Jeremy G. Owen, Robert A. Keyzers, Shinichi Sunagawa, Jörn Piel   +11 more
wiley   +2 more sources

Mechanistic Insights Into Instability From Single Void Dynamics at the Lithium Metal‐Solid Electrolyte Interface

Advanced Science, EarlyView.
Void morphology at the lithium metal‐solid electrolyte contact governs electrochemical contact stability in all‐solid‐state batteries. This work resolves the competing roles of electrochemical reaction, bulk vacancy diffusion, and distinct surface diffusion pathways in dictating the size and morphology evolution of a single void and its transition to a
Sourim Banerjee, Bairav S. Vishnugopi, Guang Lin, Partha P. Mukherjee   +3 more
wiley   +1 more source

Orchestrating Anion–π+ Interactions to Accelerate Metal‐Free Room‐Temperature Phosphorescence

Angewandte Chemie, EarlyView.
Tuning anion–π+ interactions in pyridinium iodide contact ion pairs enables ultrafast metal‐free room‐temperature phosphorescence (540–605 nm) with radiative rates up to 5.2×105 s−1. Strong iodide→π+ charge‐transfer coupling, enhanced spin–orbit interactions, and dynamic ion‐pair organization accelerate intersystem crossing and emission, establishing ...
Eetu Hakkarainen, Corentin Montagne, Hao‐Cheng Lin, Chen‐Yu Lin, Khai‐Nghi Truong, Po‐Yu Chen, Anton Nechaev, Fabien B. L. Cougnon, Igor O. Koshevoy, Toni Eskelinen, Hao‐Wu Lin, Pi‐Tai Chou, Andrey Belyaev   +12 more
wiley   +2 more sources

Phosphor‐Sensitized Ternary Organic Solar Cells Achieving 18.6% PCE via Ir(III)‐Mediated Triplet Energy Transfer and Non‐Radiative Recombination Suppression

Advanced Science, EarlyView.
A synergistic phosphor‐sensitization strategy (PSS) significantly enhances ternary OSCs performance. By integrating an Ir‐3 complex as a triplet energy mediator within a pyrazine‐based (N2) ternary blend (PM6:N2: L8‐BO) doped with 1 wt.% of Ir‐3 complex, and a PCE of 18.6% is achieved through efficient triplet‐triplet energy transfer (TTET), suppressed
Priyanka Yadav, Guohong Liu, Hyerin Kim, Songhyun Kim, Minsung Kim, Yeongbin Ma, Jisan Lim, Young Yong Kim, Taehyung Jang, Raja Kumaresan, Jinhwan Yoon, Sung‐Ho Jin   +11 more
wiley   +1 more source

One‐Step Access to Ultra‐Bright Macrocyclic Oligo‐BODIPYs Featuring Long‐Lived Cyclic Excitons

Angewandte Chemie, EarlyView.
Strong Fluorescence Meets Long Lifetimes: A template‐free, one‐step synthesis affords a series of methylene‐bridged macrocyclic oligo‐BODIPYs combining strong fluorescence with exceptionally long fluorescence lifetimes. Steady‐state and time‐resolved optical spectroscopy reveal unique excitonic coupling conditions and unusual size‐dependent ...
Lukas J. Patalag, Atanu Patra, Mike Pauls, Roland Wilcken, Yuriy Kononevich, Nils van Staalduinen, Peter G. Jones, Andreas Steffen, Thorben Cordes, Christoph Bannwarth, Daniel B. Werz   +10 more
wiley   +2 more sources

Gaussian Process Regression–Neural Network Hybrid with Optimized Redundant Coordinates: A New Simple Yet Potent Tool for Scientist's Machine Learning Toolbox

Advanced Intelligent Discovery, EarlyView.
A machine learning method, opt‐GPRNN, is presented that combines the advantages of neural networks and kernel regressions. It is based on additive GPR in optimized redundant coordinates and allows building a representation of the target with a small number of terms while avoiding overfitting when the number of terms is larger than optimal.
Sergei Manzhos, Manabu Ihara
wiley   +1 more source