Results 71 to 80 of about 41,533 (292)

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

open access: yesAdvanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li   +16 more
wiley   +1 more source

Proposals for Next-Generation Eco-Friendly Non-Flammable Refrigerants for a −100 °C Semiconductor Etching Chiller Based on 4E (Energy, Exergy, Environmental, and Exergoeconomic) Analysis

open access: yesEnergies
Recent advancements in cryogenic etching, characterized by high aspect ratios and etching rates, address the growing demand for enhanced performance and reduced power consumption in electronics. To precisely maintain the temperature under high loads, the
Hye-In Jung   +2 more
doaj   +1 more source

Single- and two-photon absorption laser-induced fluorescence spectroscopy in rare gases for gridded ion thruster diagnostics

open access: yesEPJ Techniques and Instrumentation, 2022
Methods based on laser-induced fluorescence spectroscopy are widely used for spatially resolved non-intrusive diagnostics of atomic or molecular densities and velocity distributions in plasma applications.
Christoph Eichhorn   +6 more
doaj   +1 more source

LANGUAGE FORM USED IN EFL COURSEBOOK “PASSPORT TO THE WORLD” [PDF]

open access: yes, 2017
Published EFL coursebooks are normally written by experienced and well- qualified peopleand the material contained in them is usually carrefully tested in pillot studies in actualteaching situations before publication. Todays, many EFL coursebooks in the
Nenotek, Seprianus A.
core  

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

open access: yesAdvanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil   +7 more
wiley   +1 more source

THE INTEREST AND POETRY WRITING SKILLS IMPROVEMENT BY DISCOVERY BASED LEARNING METHOD [PDF]

open access: yes, 2017
This study aimed: 1) to increase the interest in writing poems; and 2) to improve the ability to write poetry in grade VIII. This research was a classroom action research.
Rahayu, Erni
core  

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

open access: yesAdvanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang   +10 more
wiley   +1 more source

Spectroscopic studies on the enhanced radiation with high Z rare gas seeding for mitigating divertor heat loads in LHD plasmas

open access: yesNuclear Materials and Energy, 2019
We have measured extreme ultraviolet (EUV) and soft X-ray emission spectra of krypton (Kr) ions in the Large Helical Device (LHD) plasmas with Kr gas seeding intended for mitigating divertor heat loads.
C. Suzuki   +6 more
doaj   +1 more source

THE ROLE OF LOCAL LANGUAGE IN NATION’S CHARACTER BUILDING* [PDF]

open access: yes, 2017
There are much complex cultures appeared as the result of “paradigm process in a modern era. New dimensions are fruitful until all experiences and sciences become relative because they tend to be the result of human activity.
Citraresmana, Elvi   +2 more
core  

Direct observation of atomic diffusion in warm rubidium ensembles

open access: yes, 2013
We present a robust method for measuring the diffusion coefficients of warm atoms in buffer gases. Using optical pumping, we manipulate the atomic spin in a thin cylinder inside the cell.
Parniak, Michal, Wasilewski, Wojciech
core   +1 more source

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