Results 91 to 100 of about 1,660 (149)

定量动态增强MRI在脑高低级别胶质瘤术前病理分级中的应用研究

open access: yesZhongguo shiyan zhenduanxue, 2016
目的探讨定量动态增强MRI(T1-DCE MRI)在脑高低级别胶质瘤术前病理分级中的应用价值。方法选择经手术病理证实的30例脑胶质瘤患者为研究对象,其中低级别(WHOⅠ、Ⅱ级)胶质瘤15例,高级别(WHOⅢ、Ⅳ级)胶质瘤15例。全部病例均行3T常规MR增强及MR灌注成像检查,原始灌注图像数据经工作站软件处理,构建容量转移常数(Ktrans)、回流速率常数(Kep)、血管外细胞外容积分数(Ve)图,选择ROI,计算Ktrans、Kep和Ve值。高低级别胶质瘤Ktrans ...
赵明   +6 more
doaj  

Evaluation of dynamic contrast-enhanced MRI biomarkers for stratified cancer medicine: How do permeability and perfusion vary between human tumours?

open access: yes, 2018
BACKGROUND: Solid tumours exhibit enhanced vessel permeability and fenestrated endothelium to varying degree, but it is unknown how this varies in patients between and within tumour types.
John C. Waterton   +38 more
core   +1 more source

Results of Spearman's correlation tests between Ktrans and 18F-FDG-PET parameters in lymph nodes (N = 45).

open access: yes, 2020
Results of Spearman's correlation tests between Ktrans and 18F-FDG-PET parameters in lymph nodes (N = 45).
Emanuela Ruberto (8520150)   +12 more
core   +1 more source

Voxel-wise tracer kinetic model selection for DCE-MRI measurements of blood-brain barrier leakage

open access: yes
Purpose To apply voxel-wise tracer kinetic model selection, characterise the spatial distribution of best-fitting models across the brain, and evaluate whether model selection improves sensitivity for differentiating normal-appearing tissue from ...
Parkes, Laura M.; id_orcid   +5 more
core   +1 more source

Acquisition of Ktrans perfusion parameter maps from DCE-MRI in breast cancer using a deep learning approach

open access: yesQuantitative Imaging in Medicine and Surgery
Traditional methods for calculating perfusion parameter maps such as Ktrans require significant computational resources and time, leading to errors due to the variety of analysis models and the difficulty in estimating the arterial input function (AIF). Thus, it is difficult to apply Ktrans measurements to clinical diagnosis.
Li, Jingfei   +14 more
openaire   +3 more sources

Dynamic multi-echo DCE- and DSC-MRI in rectal cancer: Low primary tumor Ktrans and ΔR2* peak are significantly associated with lymph node metastasis.

open access: yesJournal of magnetic resonance imaging : JMRI, 2017
To implement a dynamic contrast-based multi-echo MRI sequence in assessment of rectal cancer and evaluate associations between histopathologic data and the acquired dynamic contrast-enhanced (DCE) and dynamic susceptibility contrast (DSC) -MRI parameters.This pilot study reports results from 17 patients with resectable rectal cancer.
Grøvik, Endre   +8 more
openaire   +3 more sources

Supplementary Fig. S8 from Amelioration of Tumor-promoting Microenvironment via Vascular Remodeling and CAF Suppression Using E7130: Biomarker Analysis by Multimodal Imaging Modalities

open access: yes
ktrans and apparent diffusion coefficient (ADC) values in xenografted ...
Taro Semba (15054098)   +10 more
core   +1 more source

Supplementary Figure 1 from Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV

open access: yes, 2012
PDF file, 46K, Quantification of color coded Ktrans and ve parametric images following DCE-MRI.
Kimerly Powell (14988285)   +14 more
core   +1 more source

Optimising use of precision data of the DCE-MRI quantitative imaging biomarker Ktrans for clinical trials

open access: yes
Assessment of early biological response to therapy is a central challenge in oncology, with implications for both clinical trial efficiency and personalized patient management.
Sridharan, N
core  

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