Results 121 to 130 of about 1,660 (149)

Flow versus permeability weighting in estimating the forward volumetric transfer constant (Ktrans) obtained by DCE-MRI with contrast agents of differing molecular sizes

Magnetic Resonance Imaging, 2017
To quantify the differential plasma flow- (Fp-) and permeability surface area product per unit mass of tissue- (PS-) weighting in forward volumetric transfer constant (Ktrans) estimates by using a low molecular (Gd-DTPA) versus high molecular (Gadomer) weight contrast agent in dynamic contrast enhanced (DCE) MRI.DCE MRI was performed using a 7T animal ...
Cheng-He Li, Fang-Hsin Chen, Dawid Schellingerhout, Yu-Shi Lin, Ji-Hong Hong, Ho-Ling Liu   +5 more
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Computed tomography–derived Ktrans and serum S100B in quantitative evaluation of blood–brain barrier permeability in traumatic brain injury

Neuroradiology
Traumatic brain injury (TBI) often leads to blood-brain barrier (BBB) disruption, contributing to secondary brain damage. Perfusion computed tomography (PCT) may assess BBB permeability through the transfer constant (Ktrans), while serum S100 calcium-binding protein B (S100B) serves as a biomarker of BBB integrity. However, the relationship between PCT
Jakob, Meglič, Katarina, Šurlan Popović, Fajko F, Bajrović, Primož, Gradišek, Jasna, Rapnik, Jernej, Avsenik   +5 more
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Ktrans Applications In Neurorradiology

Learning objectives: The objective of this poster is to review the applications of the volume transfer constant (Ktrans), a quantitative biomarker derived from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), in evaluating blood-brain barrier (BBB)...
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Dynamic contrast enhanced MRI (DCE MRI) for assessment of effects of anti-angiogenic therapy: Comparison of the transfer constant (Ktrans) to blood flow and permeability derived by a distributed parameters model

Journal of Clinical Oncology, 2007
14109 Background: Transfer constant (Ktrans) and IAUC60 normalized with arterial input function are commonly used dynamic contrast enhanced magnetic resonance imaging (DCE MRI) parameters. The distributed parameters model (DP) is a DCE MRI model that enables derivation of blood flow and capillary permeability-surface area product (PS).
C. H. Thng, T. S. Koh, H. Rumpel, J. B. Khoo, A. B. Ong, N. Sukri, B. C. Tai, R. A. Soo, R. Humerickhouse, B. C. Goh   +9 more
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A comparison of K^trans measurements obtained with conventional and first pass pharmacokinetic models in human gliomas

Journal of Magnetic Resonance Imaging, 2004
AbstractPurposeTo compare in a group of patients with cerebral gliomas the estimates of Ktrans between a conventionally established pharmacokinetic model and a recently developed first pass method.Materials and MethodsGlioma patients (23) were studied using T1‐weighted dynamic contrast‐enhanced magnetic resonance imaging (MRI), and two alternative ...
Haroon, Hamied A., Buckley, David L., Patankar, Tufail A., Dow, Graham R., Rutherford, Scott Alexander, Balériaux, Danielle, Jackson, Alan   +6 more
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Dynamic contrast enhanced MRI (DCE MRI) for Phase I anti-angiogenic trial: Comparison of the transfer constant (Ktrans) to blood flow and permeability derived by a distributed parameter model

Journal of Clinical Oncology, 2008
3514 Background: The distributed parameter (DP) model is a DCE-MRI model that enables derivation of blood flow and capillary permeability-surface area product (PS).
C. H. Thng, S. Hartono, T. S. Koh, H. Rumpel, A. B. Ong, N. Sukri, B. C. Tai, R. A. Soo, R. Humerickhouse, B. C. Goh   +9 more
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The crystal structure of potassium trans(O6)-1,3-propanediamine-N,N'-diacetato-N,N'-di-3-propionatocobaltate(III) trihydrate and consideration of ring strain, Ktrans(O6)-[Co(1,3-pddadp)] · 3H2O

Inorganica Chimica Acta, 1996
Abstract The crystal structure of Krans(O6)-[Co(1,3-pddadp)] · 3H2O(1,3-pddadp = 1,3-propanediamine-N,N'-diacetate-N,N'-di-3- propionate ion) was determined by single crystal X-ray diffraction techniques. The complex anion is a trans(O6) isomer in which the cobalt(III) ion is surrounded octahedrally by the two nitrogen and four oxygen atoms of 1,3 ...
Masood Parvez, Chris Maricondi, Dušan J. Radanović, Srećko R. Trifunović, V.D. Miletić, Bodie E. Douglas   +5 more
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A Ktrans deep characterization to measure clinical significance regions on prostate cancer

15th International Symposium on Medical Information Processing and Analysis, 2020
Yesid Gutiérrez, John Arevalo, Fabio Martinez   +2 more
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Perfusion CT derived Ktrans as a predictor of secondary brain injury following traumatic brain injury

Purpose Methods and materials Results Conclusion Personal information and conflict of interest ...
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Microvascular permeability parameters(Ktrans,Ve)in glioma grading and correlation analysis with intratumoral susceptibility signal intensity（ITSS）on HR-SWI

2014
Aims and objectives Methods and materials Results Conclusion Personal information ...
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