Results 41 to 50 of about 10,677 (169)

Discriminator‐Guided Inverse Folding for Multi‐Property Protein Design

Advanced Science, EarlyView.
Discriminator‐Guided Inverse Folding (DGIF) integrates multiple property predictors trained from single‐property datasets to guide protein sequence generation from a backbone structure. DGIF enables simultaneous improvement of thermostability and solubility without requiring multi‐property annotated datasets and generates designs that move toward the ...
Yuchuan Zheng, Chuyi Liu, Zhaoming Liu, Mao Su, Chenyu Tang, Xiang Zheng, Hao Zhang, Jingyuan Li   +7 more
wiley   +1 more source

f-divergence Analysis of Generative Adversarial Network

Foundations of Computing and Decision Sciences
We aim to establish estimation bounds for various divergences, including total variation, Kullback-Leibler (KL) divergence, Hellinger divergence, and Pearson χ2 divergence, within the GAN estimator.
Hasan Mahmud, Sang Hailin
doaj   +1 more source

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Rényi Entropy and Rényi Divergence in Product MV-Algebras

Entropy, 2018
This article deals with new concepts in a product MV-algebra, namely, with the concepts of Rényi entropy and Rényi divergence. We define the Rényi entropy of order q of a partition in a product MV-algebra and its conditional version ...
Dagmar Markechová, Beloslav Riečan
doaj   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Uniqueness and Optimality of Dynamical Extensions of Divergences

PRX Quantum, 2021
We introduce an axiomatic approach for channel divergences and channel relative entropies that is based on three information-theoretic axioms of monotonicity under superchannels, i.e., generalized data processing inequality, additivity under tensor ...
Gilad Gour
doaj   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

An Introduction to Predictive Processing Models of Perception and Decision‐Making

Topics in Cognitive Science, EarlyView., 2023
Abstract The predictive processing framework includes a broad set of ideas, which might be articulated and developed in a variety of ways, concerning how the brain may leverage predictive models when implementing perception, cognition, decision‐making, and motor control.
Mark Sprevak, Ryan Smith
wiley   +1 more source

Information theoretical approach to detecting quantum gravitational corrections

Journal of High Energy Physics
In this paper, we investigate the scales at which quantum gravitational corrections can be detected in a black hole using information theory. This is done by calculating the Kullback-Leibler divergence for the probability distributions obtained from the ...
Behnam Pourhassan, Xiaoping Shi, Salman Sajad Wani, Saif-Al-Khawari, Farideh Kazemian, İzzet Sakallı, Naveed Ahmad Shah, Mir Faizal   +7 more
doaj   +1 more source

Efficient In‐Hardware Matrix–Vector Multiplication and Addition Exploiting Bilinearity of Schottky Barrier Transistors Processed on Industrial FDSOI

Advanced Electronic Materials, EarlyView.
ABSTRACT Machine learning and Artificial Intelligence (AI) tasks have stretched traditional hardware to its limits. In‐hardware computation is a novel approach that aims to run complex operations, such as matrix–vector multiplication, directly at the device level for increased efficiency.
Juan P. Martinez, Niladri Bhattacharjee, Yuxuan He, Giulio Galderisi, Brojogopal Sapui, Sara Mannaa, Ian O'Connor, Violetta Sessi, Peter Javorka, Thomas Mikolajick, Jens Trommer   +10 more
wiley   +1 more source