Results 141 to 150 of about 43,659 (221)
RNA‐based CLEM (RCLEM) bridging RNA localisation and ultrastructural mapping in 3D
Journal of Microscopy, Volume 303, Issue 1, Page 120-131, July 2026.Abstract Spatial transcriptomics and in situ hybridisation techniques have become essential for contextualising single‐cell RNA sequencing (scRNA‐seq) data by mapping cell type– and state–specific mRNA expression within intact tissues. Beyond validating scRNA‐seq predictions, these spatial methods provide critical insight into the localisation of ...
Daan Verhaege +8 more
wiley +1 more source
Targeting Kupffer Cell Enolase 1 Attenuates Liver Inflammation and Injury in Hemorrhagic Shock. [PDF]
Int J Mol SciHu Z, Li J, Rashid N, Jacob A, Wang P.
europepmc +1 more source
From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells
Journal of Microscopy, Volume 303, Issue 1, Page 3-20, July 2026.Abstract The secretory pathway is a central and evolutionarily conserved feature of eukaryotic cells, responsible for protein and lipid trafficking, membrane biogenesis, signalling, and cellular homeostasis. Its complexity, dynamic behaviour, and nanoscale organisation have made it a longstanding target of microscopy‐driven investigation.
Charlotte Pain, Emily Farley
wiley +1 more source
Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure
Liver International, Volume 46, Issue 7, July 2026.ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli +5 more
wiley +1 more source
Kupffer Cell-Derived Interleukin-6 Aggravates Radiation-Induced Liver Disease by Activating Hepatocyte STAT3 to Promote <i>Ccng1</i> Transcription. [PDF]
Adv Radiat OncolSong X +8 more
europepmc +1 more source
Effect of Interferon Gamma on Ebola Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line. [PDF]
Viruses, 2023 Aguilar-Briseño JA +6 more
europepmc +1 more source
Physiological Reports, Volume 14, Issue 13, July 2026.Abstract This study investigated the combined effects of alcohol and sugar, termed sweetened alcohol consumption (SAC), and tannic acid (TA) intervention on hepatic health in adolescent rats. Sixty‐four male and female 42‐day‐old Sprague–Dawley rats were assigned to control, TA (50 mg/kg), SAC (10% ethanol +20% fructose), or SAC+TA groups and treated ...
Toluwase E. Olanipekun +4 more
wiley +1 more source
HFE-Related Hemochromatosis May Be a Primary Kupffer Cell Disease. [PDF]
BiomedicinesKouroumalis E +2 more
europepmc +1 more source
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.Integrated transcriptomic, single‐cell, pseudotime, cell–cell communication, human tissue, and in vivo analyses define a dynamic four‐gene axis across the MASLD continuum. Progressive CYP2C19 downregulation and AKR1B10, COL1A2, and SPP1 upregulation link metabolic dysfunction to disease progression, while AKR1B10 knockdown or CYP2C19 overexpression ...
Kejun Liu +5 more
wiley +1 more source