Results 151 to 160 of about 1,710,062 (294)

Initial magnetic resonance imaging/magnetic resonance angiography may miss intracranial artery dissection in young adults with stroke: the role of subsequent imaging. [PDF]

Eur Stroke J
Makita N, Ohara T, Makino M, Tanaka E, Fukunaga D, Tokuda N, Fujii A, Takezawa H, Imai K, Yamada T, Nagakane Y, Ogura S, Maezono-Kandori K, Mizuno T.   +13 more
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

HIF-PH Inhibitor Promotes Stabilization of HIF-1α via Inhibition of Its Degradation and Exerts Chondroprotective Effects in a Rat Osteoarthritis Model. [PDF]

Int J Mol Sci
Nakamura K, Fujii Y, Arai Y, Nakagawa S, Inoue A, Cha R, Sugie K, Hayashi K, Saito T, Kishida T, Mazda O, Takahashi K.   +11 more
europepmc   +1 more source

Reversing Temozolomide Resistance in Glioblastoma Based on Cuproptosis‐Mediated Positive Feedback Loop

Advanced Science, EarlyView.
To effectively reverse TMZ resistance, this work proposes a cuproptosis‐mediated positive feedback loop that integrates mitochondrial dysfunction, ATP depletion, AMPK‐p53 signaling, and glycolytic inhibition, ultimately amplifying cell death. This cuproptosis‐mediated feedback loop simultaneously disrupts multiple resistance pathways in GBM, including ...
Wenjie Feng, Rui Yang, Chang Weng, Chen Li, Wanrui Shi, Yang Chen, Yang Yang, Yi Liu, Pengfei Ge, Hao Zhang   +9 more
wiley   +1 more source

Back to Kyoto? US Participation and the Linkage between R&D and Climate Cooperation [PDF]

The US decision not to ratify the Kyoto Protocol and the recent outcomes of the Bonn and Marrakech Conferences of the Parties drastically reduces the effectiveness of the Kyoto Protocol in controlling GHG emissions.
Carlo Carraro, Igor Cersosimo, Carmen Marchiori, Barbara Buchner   +3 more
core  

Inhibition of CDK/Cyclin-phospho-Rb signaling by amebaciclib may have an antitumor effect against uterine leiomyosarcoma. [PDF]

Signal Transduct Target Ther
Hayashi T, Muto M, Konishi I.
europepmc   +1 more source

Japan's Energy Saving Policy: Historical and Legal Perspectives

Ежегодник Япония, 2022
D. V. Streltsov
doaj  

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Macroeconomic Impacts of the Clean Development Mechanism: The Role of Investment Barriers and Regulations [PDF]

This paper quantifies the macroeconomic impacts of the Clean Development Mechanism (CDM) under the Kyoto Protocol based on a computable general equilibrium (CGE) model of international trade and energy use.
Moslener, Ulf, Böhringer, Christoph, Anger, Niels   +2 more
core  

A Decade of Screening and Treating Helicobacter pylori Infection Among First-Year High School Students in Kyoto, Japan: Annual Trends in Infection, Consultation, and Eradication Success Rates (2015-2023). [PDF]

Helicobacter
Handa O, Uchiyama K, Takagi T, Naito Y.
europepmc   +1 more source