Results 61 to 70 of about 2,241,424 (335)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

The Cost of the Kyoto Protocol to U.S. Crop Production: Measuring Crop Price, Regional Acreage, Welfare, and Input Substitution Effects

Journal of Agricultural and Resource Economics, 2000
This study analyzes the impact of implementing carbon permit trading considered under the Kyoto Protocol, and the subsequent expected increase in energy and resource prices on U.S. crop production.
Kazim Konyar, Richard E. Howitt
doaj   +1 more source

Smoke and Mirrors: The Kyoto Protocol and Beyond [PDF]

The Kyoto Protocol (KP) is considered a necessary first step towards an effective future climate accord. As argued in this paper, however, the KP will likely fail because it has too many loopholes, inadequate governance structures and insufficient ...
G. Cornelis van Kooten
core  

Bubble Formation Control: Fabrication of Centimeter‐Sized Tissue‐Like Constructs by Catalase‐Coated Oxygen‐Releasing Hydrogel

Advanced Materials, EarlyView.
Oxygen‐releasing hydrogels are widely used to support cell survival in 3D cultures and to promote wound healing. However, incorporating catalase to convert H2O2 into O2 often generates additional oxygen bubbles, leading to material instability which rarely addressed.
Sukulya Bunuasunthon, Isabel F. Amaral, Ana P. Pêgo, Michiya Matsusaki   +3 more
wiley   +1 more source

Exploring the Nature of Strategic Interactions in the Ratification Process of the Kyoto Protocol [PDF]

Do countries interact when they decide whether or not to ratify the Kyoto Protocol? If so, what is the nature of these interactions? To answer these questions, we provide a theoretical analysis based on the notions of strategic substitutability and ...
Alexandre SAUQUET
core   +2 more sources

Carbon stocks in Norwegian forested systems. Preliminary data [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2000
Between 1990 and 2010 the projected emissions of greenhouse gases in Norway is assumed to increase 24%. As a signatory to the Kyoto Protocol, Norway is supposed to limit the greenhouse gas emissions in the period 2008–2012 to 1% above the 1990 level ...
Oyen BH., Eldhuset T., de Wit HA., Dalen LS., Aalde H., Kjonaas OJ.   +5 more
doaj  

Dismantling of a breakthrough: the Kyoto Protocol - just symbolic policy! [PDF]

We show that U.S. withdrawal from the Kyoto Protocol is straightforward under political economy considerations. The reason is that U.S. compliance costs exceed low willingness to pay for dealing with global warming in the U.S.
Vogt, Carsten, Böhringer, Christoph
core  

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

The Kyoto Protocol and European energy policy

European View, 2010
During the lead up to and assessment of the Copenhagen Climate Conference in November 2009, the effects of the celebrated Kyoto Protocol were often overlooked. Although the aims of the Kyoto Protocol can be relegated to the dustbin of history, the targets set out in the agreement allowed Europe to put itself in a dominant position.
DE FILIPPIS, Fabrizio, SCARANO, Giovanni
openaire   +2 more sources