Results 81 to 90 of about 1,186,422 (232)

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Influence du type de virus et de l'espèce affectée sur les lésions de la peste bovine

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1956
Aucun résumé disponible en français.
G. Thiéry
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Lésions de la peau chez le chien, le cheval et le veau causées par les stomoxes Stomoxys calcitrans (L.) (Diptera : Muscidae)

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1995
Des lésions spécifiques de la peau causées par Stomoxys calcitrans sur des sites de prédilection sont décrites sur des espèces différentes d'animaux (chiens, chevaux et veaux) consécutivement à des piqûres par des stomoxes, Une dermatite nécrotique est ...
I. Yeruham, Y. Braverman
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Une lésion ostéolytique rare de la rotule

, 2020
Il est très rare que la tuberculose (TB) soit la cause d’une lésion ostéolytique de la rotule (patella). En raison d’une présentation clinique aspécifique, d’une évolution insidieuse et de l’absence de caractéristiques radiologiques pathognomoniques, le ...
De Backer, Adelard, Vanhoenacker, Filip, Verniers, Lucas, Beekman, Pieter   +3 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Note préliminaire sur la gastrothylose des jeunes zébus à Madagascar

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1957
Aucun résumé disponible en français.
S. Grétillat
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Amibiase pulmonaire chez un zébu

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1956
Aucun résumé disponible en français.
G. Thiéry, Pierre-Claude Morel
doaj   +1 more source