Results 51 to 60 of about 51,233 (201)

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

Advanced Science, Volume 13, Issue 3, 14 January 2026.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T. Huse, Bo Chen, Timothy A. Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang   +16 more
wiley   +1 more source

A Transient Phenolate Enables Relaxation of Z‐Tetra‐ortho‐fluoroazobenzene to the Stable State in Seconds

Angewandte Chemie, Volume 137, Issue 43, October 20, 2025.
The rate of Z‐to‐E isomerization of a tetrafluoroazobenzene subunit in a spiropyran hybrid is controlled by the rate of merocyanine formation. Rate accelerations of 102–106 were observed for changes in solvent polarity, UV light irradiation and passage through silica.
William Brittain, Scott Barrett, Len Mouer, Nathalie Sauceda   +3 more
wiley   +2 more sources

Sử dụng sinh khối vi tảo biển dị dưỡng Schizochytrium để nâng cao hàm lượng docosahexaenoic acid (DHA, C22:6-3) trong trứng gà [PDF]

, 2016
The consumers’ demand for food products of superior health quality are growing. Many researches have been conducted to enhance nutritional value of foods as meat, eggs, and milk.
Anh, Hoàng Thị Lan, Huyền, Ninh Thị, Hồng, Nguyễn Thị, Hồng, Đặng Diễm, Quỳnh, Hoàng Thị Hương, Việt, Trần Quốc   +5 more
core   +2 more sources

NGHIÊN CỨU THÀNH PHẦN HÓA HỌC VÀ VI SINH VẬT CỦA RƯỢU VANG SIM THU HÁI TẠI XÃ CÔN LÔN HUYỆN NA HANG, TỈNH TUYÊN QUANG

, 2021
Rượu vang là loại đồ uống có cồn nhẹ được lên men trực tiếp từ dịch quả mà không trải qua quá trình chưng cất. Rượu vang sim rừng Na Hang được sản xuất từ dịch ép quả sim (Rhodomyrtus tomentosa) sử dụng chủng nấm men Saccharomyces cerevisiae S5 đã được ...
Lê Thị
semanticscholar   +1 more source

Comparative Phytochemical Profiles of Medicinal Plants Used for Wound Treatment: Insights From Wild and Hydroponically Cultivated Species in Lugazi Diocese, Uganda

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Medicinal plants such as Centella asiatica, Conyza sumatrensis, and Justicia betonica are widely used in Uganda for traditional wound healing. However, the impact of cultivation conditions on their therapeutic potential remains poorly understood.
Ivan Kahwa, Christina Seel, Hilda Ikiriza, Maria Kulosa, Susan Billig, Claudia Wiesner, Anke Weisheit, Olivia Harriet Makumbi, André Gerth, Leonard Kaysser   +9 more
wiley   +1 more source

Tách chiết, tinh sạch và xác định đặc tính sinh học của chất kháng nấm và chất kháng khuẩn từ chủng vi khuẩn Bacillus velezensis CP 1604 [PDF]

, 2016
Bacillus velezensis is one of the members of the Bacillus subtilis species complex which is generally considered as safety organism. The bacterium possesses several beneficial properties for crops, especially production of antifungal and antibacterial ...
Hợp, Dương Văn, Liên, Nguyễn Phương, Lương, Đào Thị, Trung, Trịnh Thành, Vân, Đinh Thị Tuyết   +4 more
core   +2 more sources

Dietary DNA Metabarcoding From Animal Fecal Samples

Current Protocols, Volume 6, Issue 1, January 2026.
Abstract Fecal DNA metabarcoding is a powerful tool for examining animal diets with unprecedented resolution, offering insights into ecological patterns shaped by trophic interactions. As a result, dietary metabarcoding has become widely applied across ecology, evolution, behavior, and conservation.
Rachel D. McConnell, Crinan Jarrett, Diogo F. Ferreira, Luke L. Powell, Alma L. S. Quiñones, Davide M. Dominoni, Andreanna J. Welch   +6 more
wiley   +1 more source

Monitoring the Prevalence and Distribution of Chytrid Fungus (Batrachochytrium dendrobatidis) in the Kihansi Spray Toad (Nectophrynoides asperginis) Population in the Kihansi Gorge Spray Wetlands, Tanzania

Ecology and Evolution, Volume 16, Issue 1, January 2026.
How to manage the continued impact of Chytrid fungus on Kihansi Spray Toad population in the wild. ABSTRACT Chytridiomycosis, caused by the fungus Batrachochytrium dendrobatidis (Bd), is fatal to some amphibian species, whereas others can carry the pathogen without developing disease.
Devolent T. Mtui, Leonard J. Haule, Joseph O. Ogutu, Asa Preston, Josephine Braun, William D. Newmark, Edward M. Kohi, Juma Kimera, Mikidadi Mtalika, Hussein Adam, Samueli Mtoka, Felix Shayo, Julius D. Keyyu, Mariam R. Makange, Jean N. Hakizimana, Gerald Misinzo, Eblate E. Mjingo   +16 more
wiley   +1 more source

Intranasal Mosaic H1N1 Live Attenuated Influenza Vaccine Elicits Broad Cross‐Reactive Immunity and Protection Against Group 1 and 2 Influenza A Viruses

MedComm, Volume 6, Issue 12, December 2025.
Our study introduces the mosaic H1N1 LAIV, an intranasal broad‐spectrum influenza vaccine that integrates the mosaic antigen design with LAIV technology. Intranasal boosting in mice elicits robust mucosal, humoral, and cellular immunity, as well as provides extensive protection against both homologous and heterologous influenza strains.
Ximeng Ma, Qi Chen, Yukun Cai, Chen Chen, Jian Lu, Zhuolin Yang, Xue Han, Liangliang Wang, Xuejie Liu, Yuhang Shi, Yuhang Zhang, Li Xin, Yihao Chen, Run Ma, Wantong Pang, Tian Bai, Yuelong Shu   +16 more
wiley   +1 more source

Hydrostatic Pressure Induces Osteogenic Differentiation of Single Stem Cells in 3D Viscoelastic Microgels

Small Science, Volume 5, Issue 12, December 2025.
Single mesenchymal stem cells are encapsulated in arginine‐glycine‐aspartic acid‐functionalized alginate microgels using a microfluidic chip. After secondary crosslinking, cells are cultured under cyclic hydrostatic pressure in a custom pressurization setup.
Nergishan İyisan, Fernando Rangel, Leonard Funke, Bingqiang Pan, Berna Özkale   +4 more
wiley   +1 more source