Results 31 to 40 of about 1,361 (131)

Relationship between age and severity of cognitive impairment at diagnosis for early‐onset and late‐onset Alzheimer's disease: Comparison of LEADS and ADNI

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
INTRODUCTION Recent work has identified unique cognitive profiles for early‐onset Alzheimer's disease (EOAD) relative to late‐onset Alzheimer's disease (LOAD), however, examination has been limited in determining whether the association between age and cognitive severity at presentation also differs across conditions.
Dustin B. Hammers, Ani Eloyan, Maryanne Thangarajah, Alexander Taurone, Sujuan Gao, Laurel Beckett, Kala Kirby, Jeffrey L. Dage, Kelly Nudelman, Paul Aisen, Rema Reman, Prashanthi Vemuri, Renaud La Joie, Alexandra Touroutoglou, Alireza Atri, David Clark, Gregory S. Day, Ranjan Duara, Neill R. Graff‐Radford, Lawrence S. Honig, David T. Jones, Joseph C. Masdeu, Mario F. Mendez, Kyle Womack, Erik Musiek, Chiadi U. Onyike, Meghan Riddle, Ian Grant, Emily Rogalski, Erik C. B. Johnson, Steven Salloway, Sharon J. Sha, Raymond Scott Turner, Thomas S. Wingo, David A. Wolk, Maria C. Carrillo, Bradford C. Dickerson, Gil D. Rabinovici, Liana G. Apostolova, LEADS Consortium, for the Alzheimer's Disease Neuroimaging Initiative   +40 more
wiley   +1 more source

Association of type 2 diabetes treatment status with in vivo biomarkers of Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The association of type 2 diabetes (T2D) treatment with Alzheimer's disease (AD) is unclear. We examined T2D treatment status in relation to amyloid beta (Aβ) burden and AD‐related downstream processes. METHODS This cross‐sectional study included 546 cognitively unimpaired adults (mean age = 64.2 ± 3.2 years, 65% women ...
Muge Akinci, Froogh Aziz, Diana Guzman, Lina Cheung, Jian X. Kong, Stephanie Silver, Joseph Eimicke, Jeanne A. Teresi, Adam M. Brickman, Patrick Lao, José A. Luchsinger   +10 more
wiley   +1 more source

A Sensory Method to Evaluate Food Texture for Oropharyngeal Dysphagia by Emulating Oral Tasks

Journal of Texture Studies, Volume 57, Issue 1, February 2026.
Oropharyngeal dysphagia (OD) impairs chewing and swallowing, requiring adapted food textures. This study presents a sensory evaluation method for texture‐modified foods based on emulating oral tasks performed by people with OD. Specific oral tasks were linked to key attributes such as hardness, adhesiveness, and residue.
Jaime Paniagua, María Teresa Murillo‐Arbizu, Kizkitza Insausti, Leyre Urtasun del Castillo, Marta Uriarte Ajona, María José Beriain, Francisco C. Ibañez   +6 more
wiley   +1 more source

High Resolution Postmortem MRI Discovers Developing Structural Connectivity in the Human Ascending Arousal Network

Human Brain Mapping, Volume 46, Issue 17, 01 December 2025.
We used high‐resolution ex vivo diffusion MRI and graph theory to analyze ascending arousal network development in fetal to adult brains, revealing increasing rostral integration postnatally and identifying the dorsal raphe nucleus and ventral tegmental area as persistent connectivity hubs from fetal stages through adulthood.
Roxane Licandro, Mark Olchanyi, Luiz F. Ferraz da Silva, Andre van der Kouwe, Camilo Jaimes, Nathan X. Ngo, William Kelley, Rebecca Folkerth, Robin L. Haynes, Brian L. Edlow, Hannah C. Kinney, Lilla Zöllei   +11 more
wiley   +1 more source

Deep Learning for Detecting Dental Plaque and Gingivitis From Oral Photographs: A Systematic Review

Community Dentistry and Oral Epidemiology, Volume 53, Issue 6, Page 617-632, December 2025.
ABSTRACT Objectives This systematic review aimed to evaluate the performance of deep learning (DL) models in detecting dental plaque and gingivitis from red, green, and blue (RGB) intraoral photographs. Methods A comprehensive literature search was conducted across Medline, Scopus, Embase, and Web of Science databases up to January 31, 2025.
Mohammad Moharrami, Elaheh Vahab, Mobina Bagherianlemraski, Ghazal Hemmati, Sonica Singhal, Carlos Quinonez, Falk Schwendicke, Michael Glogauer   +7 more
wiley   +1 more source

Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Current literature presents conflicting results regarding the impact of neuroinflammation on Alzheimer's disease (AD)‐related neurodegeneration. While some studies suggest that neuroinflammation potentiates neurodegeneration, others indicate a protective effect.
Guilherme Povala, Bruna Bellaver, Marco Antônio De Bastiani, João Pedro Ferrari‐Souza, Cristiano S. Aguzzoli, Douglas T. Leffa, Pamela C. L. Ferreira, Firoza Z. Lussier, Andreia Rocha, Hussein Zalzale, Carolina Soares, Guilherme Bauer‐Negrini, Joseph Therriault, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Cécile Tissot, Bruno Zatt, Thomas K. Karikari, Milos D. Ikonomovic, Victor L. Villemagne, Serge Gauthier, Eduardo R. Zimmer, Dana L. Tudorascu, Andrea L. Benedet, Pedro Rosa‐Neto, Tharick A. Pascoal   +26 more
wiley   +1 more source

O Jogo como um Recurso para Contextualizar a Língua de Sinais

Signum: Estudos da Linguagem, 2020
O ensino de Língua Brasileira de Sinais (Libras) pautou-se em sua oficialização pela Lei nº 10.436/2002, garantindo inclusão para e direito à comunicação da pessoa surda mediante a utilização da língua de sinais.
Nerli Nonato Ribeiro Mori, Joicemara Severo Silveira, Aline Keryn Pin   +2 more
doaj   +1 more source

Differences in baseline cognitive performance between participants with early‐onset and late‐onset Alzheimer's disease: Comparison of LEADS and ADNI

Alzheimer's &Dementia, Volume 21, Issue 1, January 2025.
Abstract INTRODUCTION Early‐onset Alzheimer's disease (EOAD) and late‐onset Alzheimer's disease (LOAD) share similar amyloid etiology, but evidence from smaller‐scale studies suggests that they manifest differently clinically. Current analyses sought to contrast the cognitive profiles of EOAD and LOAD.
Dustin B. Hammers, Ani Eloyan, Maryanne Thangarajah, Alexander Taurone, Laurel Beckett, Sujuan Gao, Angelina J. Polsinelli, Kala Kirby, Jeffrey L. Dage, Kelly Nudelman, Paul Aisen, Rema Reman, Renaud La Joie, Julien Lagarde, Alireza Atri, David Clark, Gregory S. Day, Ranjan Duara, Neill R. Graff‐Radford, Lawrence S. Honig, David T. Jones, Joseph C. Masdeu, Mario F. Mendez, Kyle Womack, Erik Musiek, Chiadi U. Onyike, Meghan Riddle, Ian Grant, Emily Rogalski, Erik C. B. Johnson, Steven Salloway, Sharon J. Sha, Raymond Scott Turner, Thomas S. Wingo, David A. Wolk, Maria C. Carrillo, Bradford C. Dickerson, Gil D. Rabinovici, Liana G. Apostolova, the LEADS Consortium 1 for the Alzheimer's Disease Neuroimaging Initiative   +39 more
wiley   +1 more source

Contribuições de fatores sócio-interacionistas na escrita de surdos

Revista Educação Especial, 2012
Este artigo mostra em que os fatores sócio-interacionistas oferecidos pelo meio escolar – língua de sinais, conhecimento sistêmico, conhecimento de organização textual, conhecimento de mundo, prática sociais, instrutor de língua de sinais, professor e/ou
Patrícia Farias Fantinel, Elisane Maria Rampelotto   +1 more
doaj   +3 more sources

Visualizando a elaboração da linguagem em surdos bilíngues por meio da ressonância magnética funcional

Revista Brasileira de Linguística Aplicada
As línguas de sinais são línguas naturais que compartilham as propriedades das línguas orais. Este estudo buscou visualizar as áreas corticais ativadas em surdos bilíngues em Língua Brasileira de Sinais e em Língua Portuguesa.
Michelle Nave Valadão, Myriam de Lima Issac, Sara Regina Escorsi Rosset, Draulio Barros de Araujo, Antonio Carlos dos Santos   +4 more
doaj   +1 more source