Results 31 to 40 of about 234,030 (235)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Pengalaman Penderita Lupus Dalam Menjalani Pengobatan di Era Pandemi Covid-19

Jurnal Kesehatan, 2022
The pandemic situation causes more severe pressure on patients with lupus in undergoing treatment. The purpose of this study is to describe the experience of lupus sufferers during the treatment process during the pandemic period.
Intan Mardhanti Pracylyaningroom, Sri Lestari   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Lúpus eritematoso sistêmico: tratamento do acometimento cutâneo/articular

Revista Brasileira de Reumatologia, 2004
DESCRIÇÃO DO MÉTODO DE COLETA DE EVIDÊNCIAS: Oito reumatologistas que trabalham em serviços que atendem grande número de pacientes com lúpus eritematoso sistêmico, alguns dos quais têm pesquisa e publicações científicas nesta área, foram convidados a ...
EI Sato, ED Bonfá, LTL Costallat, NA Silva, JCT Brenol, MB Santiago, JCM Szajubok, A Rachid-Filho, RT Barros, M Vasconcelos   +9 more
doaj   +1 more source

Formative research to promote lupus awareness and early screening at Historically Black College and University (HBCU) communities in South Carolina

BMC Rheumatology, 2022
Background Systemic lupus erythematosus or lupus is a severe chronic autoimmune disorder that disproportionately impacts young African Americans. Increasing lupus awareness in this high-risk group may be an effective approach to ultimately improving ...
Edith M. Williams, Joni Nelson, Diane Francis, Keesha Corbin, Gary Link, Tomika Caldwell, Gary Gilkeson   +6 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Lúpus eritematoso cutâneo: manifestações clínicas, diagnóstico diferencial e avanços terapêuticos [PDF]

O Lúpus Eritematoso Cutâneo (LEC) é uma doença inflamatória crônica caracterizada por lesões cutâneas, frequentemente associadas a manifestações sistêmicas do lúpus.
Silva, Fabrícia Araujo e, Fernandes, Fernando Henrique Pereira, Duarte, Gabriela Ugioni, Morandini Junior, Delmar Luis, Freitas, Samira Benttenmüller de, Fedeszen, Estêvão Kubit, Furtado, Nathália Lacerda, Suguiura, Caroline Mrachima, Leonhardt, Luana Bretas dos Santos, Lopes, Tatiana Moreira, Rabelo, Izabelle Catherine Silva, Pires, Maria Eugênia Machado Simões, Silva, Renato Alves da, Marques, Isabelle Araujo, Coelho, Gustavo Henrique Lopes   +14 more
core   +4 more sources

Coroidopatia no lúpus eritematoso sistêmico

Revista Brasileira de Oftalmologia
Resumo O Lúpus Eritematoso sistêmico (LES) é uma doença autoimune que pode afetar o olho de diversas formas. A coroidopatia lúpica é rara e apresenta-se com descolamento seroso de retina, descolamento do epitélio pigmentar da retina (EPR) e epiteliopatia
Aristófanes Mendonça Canamary Jr, Jacqueline Martins de Sousa, Gabriel Costa de Andrade, Heloisa Moraes do Nascimento   +3 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source