Results 181 to 190 of about 24,487,241 (258)

Differential Functional Connectivity Between Hippocampus and Prefrontal Cortex Is Associated With Heterogeneity in Open Field Exploration and Is Disrupted Following Maternal Immune Activation. [PDF]

Hippocampus
Munn RGK, Dickerson DD, Wolff AR, Bilkey DK.   +3 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Evaluating the Solvent and pH Effect in the Inversion of the Circular Dichroism Signal of S-Naproxen. [PDF]

Chirality
Santana LC, de Faria Franca E, Ximenes VF, de Souza AR, Morgon NH.   +4 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Rapid Change of Hydrogen Neutral Energy Distribution at L/H-Transition in JFT-2M H-mode

"Rapid changes of the main ion energy distribution at transitions from L-to-H, H-to-L and during ELMs are studied with the time of flight neutral measurement on the JFT-2M tokamak.
JFT-2M, Group, "Miura, Y., Hoshino, K., Maeda, H., Itoh, K.", Itoh, S.-I., Takizuka, T., Okano, F., Mori, M., Suzuki, N.   +9 more
core  

Regulation of the growth-to-ripening transition in tomato fruits by energy charge involving SlATP-PRT and SlAPRT1. [PDF]

Mol Hortic
Liu Y, Wu P, Li B, Bian Z, Qu G, Fu D, Zhu H, Luo Y, Wang W, Zhu B.   +9 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Atomic-scale mechanism of anisotropic ion migration in 2D Bi₂O₂Se nanodevices. [PDF]

Nat Commun
Qu K, Zhang J, Chen J, Yao C, Zeng J, Wang H, Xin T, Chen WT, Chu YH, Liu P, Huang R, Cheng Y, Yang Z, Yang H, Duan C, Gao P.   +15 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

6.1% Volumetric Negative Thermal Expansion Induced by the Reversible Reconstructive Phase Transition in Pb-Free Bi_1- _xLn_xCoO₃ (Ln: Lanthanoid). [PDF]

Adv Sci (Weinh)
Sakai Y, Takahashi K, Wakazaki S, Nishikubo T, Miyake J, Koike T, Nagase T, Yamamoto T, Hatayama K, Mizumaki M, Azuma M.   +10 more
europepmc   +1 more source