Results 51 to 60 of about 409 (115)

Analysis of creatine metabolism and metabolites using gas chromatograpy – mass spectrometry.

, 2014
Creatine and phosphocreatine play an essential role in energy storage and transmission in several tissues. Two enzymes are involved in creatine biosynthesis: arginine:glycine amidinotransferase, which converts arginine and glicine to ornithine and ...
Banytė, Milda,
core  

Arsenic metabolism and creatine synthesis.

, 2014
(A) Guanadinoacetate methyltransferase (GAMT) and phosphatidyl ethanolamine methyltransferase (PEMT), which catalyze the synthesis of creatine (Cr) and phosphatidylcholine, are the major consumers of S-adenosylmethionine (SAM). Arsenic methyltransferase (
Tariqul Islam (29964), Diane Levy (13137), Brandilyn A. Peters (667608), Megan N. Hall (161611), Y. Dana Neugut (667609), Xinhua Liu (13131), Pam Factor-Litvak (13138), Joseph H. Graziano (13139), Vesna Slavkovich (13135), Vesna Ilievski (13134), Mary V. Gamble (13130), J. Richard Pilsner (13133)   +11 more
core   +1 more source

The Journal of Physiology Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake

, 2020
Key points • Creatine (Cr) plays an important role in muscle energy homeostasis as a substrate in the creatine kinase phosphoryl exchange reaction, but the consequences of creatine depletion are incompletely understood.
H E Kan, D Isbrandt, A Veltien, G J Kemp, C I Nabuurs, C U Choe, A Heerschap, R J T Rodenburg, L J C Van Loon, J Matschke, B Wieringa   +10 more
core  

Does maternal-fetal transfer of creatine occur in pregnant sheep?

, 2017
Our aim was to determine the disposition of creatine in ovine pregnancy and whether creatine is transferred across the placenta from mother to fetus. Pregnant ewes received either 1) a continuous intravenous infusion of creatine monohydrate or saline ...
Stacey Ellery, Richard Harding, Robert De Matteo, Nadia Hale, Hayley Dickinson, Clinton R. Bruce, Syed Baharom, Greg M. Kowalski, Paul Della Gatta, Rodney J. Snow, David Walker   +10 more
core   +1 more source

Inborn errors of creatine metabolism and epilepsy

, 2013
Creatine metabolism disorders include guanidinoacetate methyltransferase (GAMT) deficiency, arginine:glycine amidinotransferase (AGAT) deficiency, and the creatine transporter (CT1-encoded by SLC6A8 gene) deficiency.
Roberta Battini, Giovanni Cioni, LEUZZI, Vincenzo, MASTRANGELO, Mario   +3 more
core   +1 more source

Evidence of an intracellular creatine-sensing mechanism that modulates creatine biosynthesis via AGAT expression in human HAP1 cells. [PDF]

Sci Rep, 2023
Tropak MB, Tkachyova I, Gu R, Lee A, Schulze A.   +4 more
europepmc   +1 more source

Treatment Monitoring of Brain Creatine Deficiency Syndromes: a 1H and 31P MR Spectroscopy Study

, 2007
BACKGROUND AND PURPOSE: Brain creatine (Cr) deficiencies (BCr-d) are rare disorders of creatine biosynthesis and transport. We performed consecutive measures of total Cr (tCr) and of its phosphorylated fraction, phosphocreatine (PCr), in the brains of ...
TOSETTI M, ALESSANDRI' MG, CIONI G., BIANCHI MC, CARDUCCI, Claudia, BATTINI R, LEUZZI, Vincenzo, ANTONOZZI, Italo   +7 more
core   +1 more source

Lysine and homoarginine are closely interrelated metabolites in the rat. [PDF]

Amino Acids, 2022
Baskal S, Dimina L, Tsikas SA, Mosoni L, Remond D, Mariotti F, Tsikas D.   +6 more
europepmc   +1 more source

Maternal dietary creatine supplementation does not alter the capacity for creatine synthesis in the newborn spiny mouse

, 2013
We have previously reported that maternal creatine supplementation protects the neonate from hypoxic injury. Here, we investigated whether maternal creatine supplementation altered expression of the creatine synthesis enzymes (arginine:glycine ...
S Ellery (13647643), D La Rosa (13714216), D Walker (7836281), Rod Snow (13091994), Bree Aimee O'Connell (13052877), H Dickinson (13122063), Z Ireland (13678990)   +6 more
core  

The effects of a comparatively higher dose of 1000 mg/kg/d of oral L- or D-arginine on the L-arginine metabolic pathways in male Sprague-Dawley rats. [PDF]

PLoS One, 2023
Kim DR, Martin S, Desai K.
europepmc   +1 more source