Results 41 to 50 of about 409 (115)

Aspects of human uterine creatine metabolism during the menstrual cycle and at term pregnancy

, 2023
Creatine metabolism likely contributes to energy homeostasis in the human uterus, but whether this organ synthesizes creatine and whether creatine metabolism is adjusted throughout the menstrual cycle and with pregnancy are largely unknown.
Stacey J Ellery (13364223), Lois A Salamonsen (10002500), Mamatha Philip (17096194), Nadia Bellofiore (9923225), Kirsten R Palmer (13465095), Paul Della Gatta (13088706), Rodney J Snow (14477304), Damien Callahan (13065873)   +7 more
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Untersuchungen zur Expression von AGAT, GAMT und Ct1 in Knockout-Mausmodellen

, 2023
Bei der endogenen Synthese von Cr und beim Transport von Cr aus der Zelle heraus bzw. in die Zelle hinein sind die zwei Enzyme L-Arginin:Glycin-Amidinotransferase (AGAT) und Guanidinoacetat-Methyltransferase (GAMT) sowie der Kreatintransporter (Ct1 ...
Ahadi, Schabira
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Cerebral creatine deficiency syndromes: 13 years experience in Portugal [PDF]

, 2017
Os síndromes da deficiência em creatina cerebral são um grupo de erros inatos do metabolismo da creatina que incluem as deficiências de síntese da creatina: arginina:glicina amidinotransferase (AGAT) e S-adenosil- L-metionina:guanidinoacetato ...
Lopes, Altina, Vilarinho, Laura, Valongo, Carla   +2 more
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Master of Science [PDF]

, 2011
thesisCreatine is necessary to transfer energy between cellular compartments. Creatine is converted to phosphocreatine by the creatine kinase reaction within mitochondria and phosphocreatine generates adenosine triphosphate (ATP) in the cytoplasm.
Bentley, Rebecca L.
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Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free L-arginine in humans

, 2015
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis, whereas l-arginine (Arg) and l-homoarginine (hArg) serve as substrates for NO synthesis.
Schneider, Jessica Y., Lücke, Thomas, Chobanyan-Juergens, Kristine, Huneau, Jean-François, Kayacelebi, Arslan Arinc, Choe, Chi-Un, Atzler, Dorothee, Schwedhelm, Edzard, Langen, Jennifer, Frölich, Juegen C., Mariotti, François, Rothmann, Sabine, Weigt-Usinger, Katharina, Tsikas, Dimitrios   +13 more
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Ammonium alters creatine transport and synthesis in a 3D culture of developing brain cells, resulting in secondary cerebral creatine deficiency

, 2008
Hyperammonemic disorders in pediatric patients lead to poorly understood irreversible effects on the developing brain that may be life-threatening. We showed previously that some of these NH4+-induced irreversible effects might be due to impairment of ...
Honegger, P, Henry, H, Monnet-Tschudi, F, Cagnon, L, Wallimann, T, Braissant, O, Speer, O   +6 more
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Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake

, 2013
Contains fulltext : 118302.pdf (Publisher’s version ) (Closed access)Creatine (Cr) plays an important role in muscle energy homeostasis by its participation in the ATP-phosphocreatine phosphoryl exchange reaction mediated by creatine ...
Veltien, A.A., Heerschap, A., Isbrandt, D., Veltien, A., Rodenburg, R.J.T., Choe, C.U., Rodenburg, R. J., Loon, L.J.C. van, Wieringa, B., Kemp, G.J., van Loon, L.J.C., Nabuurs, C.I.H.C., Matschke, J., Choe, C. U., Kan, H. E., Nabuurs, C.I., Kan, H.E.   +16 more
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Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and homoarginine (hArg): the ADMA, SDMA and hArg paradoxes

, 2018
NG-Methylation of l-arginine (Arg) residues in certain proteins by protein arginine methyltransferases and subsequent proteolysis yields NG-monomethyl-l-arginine (MMA), NG,NG-dimethyl-l-arginine (asymmetric dimethylarginine, ADMA) and NG,N′G-dimethyl-l ...
Dimitrios Tsikas, Arslan Arinc Kayacelebi, Alexander Bollenbach, Erik Hanff   +3 more
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Creatine biosynthesis and transport by the term human placenta

, 2017
INTRODUCTION: Creatine is an amino acid derivative that is involved in preserving ATP homeostasis. Previous studies suggest an important role for the creatine kinase circuit for placental ATP turnover.
M Davies-Tuck (9896294), SJ Ellery (14456790), DW Walker (14471043), Greg Kowalski (13079640), Rod Snow (13091994), Clinton Bruce (13064589), PA Della Gatta (14451678), JC Mockler (15776378), P Murthi (12548320), H Dickinson (13122063)   +9 more
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Biochemical and clinical characteristics of creatine deficiency syndromes.

, 2004
Creatine deficiency syndromes are a newly described group of inborn errors of creatine synthesis (arginine:glycine amidinotransferase (AGAT) deficiency and guanidinoacetate methyltransferase (GAMT) deficiency) and of creatine transport (creatine ...
Sykut-Cegielska, Jolanta, Stöckler-Ipsiroglu, Sylvia, Mercimek-Mahmutoglu, Saadet, Gradowska, Wanda   +3 more
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