Results 81 to 90 of about 16,350,711 (297)

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Adsorbers for KMnO 4 and L-Ascorbic Acid in the Active Packaging to Prolong the Shelve-Life and Maintain the Quality of Lanzone (Lansium domesticum Corr.)Fruits

Jurnal Teknologi dan Industri Pangan, 2010
To develop an active packaging of lanzone (Lansium domisticum Corr.) Fruits, KmnO4 as an ethylene scavenger and L-ascorbic acid as an oxygent scavenger were inserted into packaging.
Soesiladi E Widodo
doaj  

Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress

BMC Complementary and Alternative Medicine, 2012
Background Ascorbic acid demonstrates a cytotoxic effect by generating hydrogen peroxide, a reactive oxygen species (ROS) involved in oxidative cell stress.
Klingelhoeffer Christoph, Kämmerer Ulrike, Koospal Monika, Mühling Bettina, Schneider Manuela, Kapp Michaela, Kübler Alexander, Germer Christoph-Thomas, Otto Christoph   +8 more
doaj   +1 more source

Changes of Ascorbic Acid Contents in Various Market Forms of Spinach (Spinacea oleracea L.) during Postharvest Storage in Light and Dark Conditions

, 2003
Changes in ascorbic acid contents in various market forms of spinach (Spinacia oleracea L.) during postharvest storage in light (20-25 μmole m^2 s^) and dark conditions were investigated.
UEDA, Yoshinori, TOLEDO, Merry Evelyn A., SHIROSAKI, Takashi   +2 more
core  

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Voltammetric Behavior of a Modified Electrode With Azide Copper Octa(3-Aminopropyl)Octasilsesquioxane Composite in the Oxidation of Ascorbic Acid

International Journal of Electrochemical Science, 2011
A novel nanostructured composite, azide copper octa (3-aminopropyl)octasilsesquioxane (ASCA) was incorporated into a graphite paste electrode and the electrochemical studies were conducted with cyclic voltammetry.
Devaney Ribeiro do Carmo, Leonardo Lataro Paim, Daniela Rodrigues Silvestrini, Acelino Cardoso de Sá, Urquisa de Oliveira Bicalho, Nelson Ramos Stradiotto   +5 more
doaj   +1 more source

Occurrence of L-Ascorbic Acid in Euglena gracilis z

, 1980
Euglena gracilis synthesizes L-ascorbic acid. The content of total L-ascorbic acid in the cells grown photoautotrophically for 9 days in the stationary phase was 4.01 μmole/10^9 cells, corresponding to 4.25 mg per g dry weight. The oxidized form, dehydro-
NAKANO, Yoshihisa, SHIGEOKA, Shigeru, KITAOKA, Shozaburo   +2 more
core  

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Sustainable recovery of lithium, nickel, manganese, and cobalt from NMC811 cathodes using propionic and ascorbic acids through optimization and kinetic analysis

Scientific Reports
An environmentally benign leaching process for recovering valuable metals from LiNi0.8Mn0.1Co0.1O2 (NMC-811) cathodes was developed using propionic acid as the leaching agent and ascorbic acid as the reducing agent.
Azadeh Yarahmadi, Hamid Reza Mortaheb, Ali Asghar Nozaeim   +2 more
doaj   +1 more source