Results 131 to 140 of about 797,532 (288)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Multitemporal Soil Moisture Retrieval From Spaceborne SAR Missions Operating at Different Frequencies

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The new Copernicus Radar Observing System for Europe in L-band (ROSE-L), expected to work in synergy with the C-band Sentinel-1 mission, will create a multiplatform Synthetic Aperture Radar (SAR) facility acquiring data in a systematic and coordinated ...
Giovanni Anconitano, Elena Arabini, Alessandro Patacchini, Mario Alberto Acuna, Nazzareno Pierdicca   +4 more
doaj   +1 more source

High-Resolution L-Band TomoSAR Imaging on Forest Canopies with UAV Swarm to Detect Dielectric Constant Anomaly. [PDF]

Sensors (Basel), 2023
Chuang HY, Kiang JF.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Incidence angle dependency and seasonal evolution of L and C-band SAR backscatter over landfast sea ice

Annals of Glaciology
We estimate sea-ice type specific incidence angle (IA) dependencies for dual polarized (HH/HV) L and C-band synthetic aperture radar (SAR) for the winter, melt onset and advanced melt seasons for level and deformed ice, using time-series of Advanced Land
Truls Karlsen, Malin Johansson, Johannes Lohse, Anthony P. Doulgeris   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Introduce Ce³⁺ Ions to Realize Enhancement of C+L Band Luminescence of KMnF₃: Yb, Er Nanoparticles. [PDF]

Nanomaterials (Basel), 2023
Cui H, Li D, Yang Y, Fu Y, Dong Y, Yin J, Qin W, Jia Z, Zhao D.   +8 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

L-Band Erbium-Doped Fiber Optimization and Transmission Investigation

Photonics
The optical spectrum resource in the C-band has been used up due to dense wavelength division multiplexing (DWDM). Because of devices’ compatibility with both the C-band and the L-band, the L-band is a good choice for further capacity expansion ...
Kaihua Hu, Li Pei, Jianshuai Wang, Zhouyi Hu, Wenxuan Xu, Long Zhang, Jing Li, Li Zhong   +7 more
doaj   +1 more source

An RFI-suppressed SMOS L-band multi-angular brightness temperature dataset spanning over a decade (since 2010). [PDF]

Sci Data, 2023
Peng Z, Zhao T, Shi J, Kerr YH, Rodríguez-Fernández NJ, Yao P, Che T.   +6 more
europepmc   +1 more source