Results 31 to 40 of about 745,558 (246)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Enhanced Coati Optimization Algorithm for Static and Dynamic Transmission Network Expansion Planning Problems

open access: yesIEEE Access
The power systems are becoming more and more complex due to the inclusion of new components and increasing load demand. Consequently, it is imperative to incorporate additional generation units and transmission links into the system. Transmission Network
Muhammet Demirbas   +2 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

L-band Airborne Repeat-pass Interferometric SAR System and Its Experimental Study

open access: yesLeida xuebao, 2019
This paper describes the L-band airborne Synthetic Aperture Radar (SAR) system and an experimental study of repeat-pass SAR interferometry. The discussions mainly focus on the internal calibration method, the imaging method based on Differential Global ...
LU Jiaguo   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Characterization of L-band synthetic aperture radar (SAR) backscatter from floating and grounded thermokarst lake ice in Arctic Alaska [PDF]

open access: yesThe Cryosphere, 2013
Radar remote sensing is a well-established method to discriminate lakes retaining liquid-phase water beneath winter ice cover from those that do not. L-band (23.6 cm wavelength) airborne radar showed great promise in the 1970s, but spaceborne synthetic ...
M. Engram   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Spatial evaluation of L-band satellite-based soil moisture products in the upper Huai River basin of China

open access: yesEuropean Journal of Remote Sensing, 2019
Using dense soil moisture (SM) measurements in the upper Huai River basin of China, this study evaluated the spatial patterns of L-band satellite-based SM products, including Soil Moisture Active Passive (SMAP) L3, Soil Moisture and Ocean Salinity (SMOS)
Liming Zhu   +3 more
doaj   +1 more source

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