Results 41 to 50 of about 745,558 (246)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A large L-band rectangular corrugated horn [PDF]

open access: yesIEEE Transactions on Antennas and Propagation, 1987
A lightweight, rectangular, corrugated-horn antenna constructed from sheet metal is described. Over a 1.3-1.7 GHz operating band, its half-power beamwidth is approximately 20\deg in the E -plane and varies from 17\deg to 13\deg in the H -plane. Quarter-wave choke slots at the aperture help to reduce the E -plane sidelobes below -55 dB at angles greater
Witebsky, C.   +3 more
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The L-Band solar flux retrieval from the Soil Moisture and Ocean Salinity (SMOS) mission: Theoretical algorithm and its validation

open access: yesJournal of Space Weather and Space Climate
The Soil Moisture and Ocean Salinity (SMOS) satellite, launched in November 2009, is equipped with the Microwave Imaging Radiometer with Aperture Synthesis (MIRAS) payload, which collects high temporal resolution polarimetric data at 1.413 GHz (L-band ...
Crapolicchio Raffaele   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Benchmarking the Retrieval of Biomass in Boreal Forests Using P-Band SAR Backscatter with Multi-Temporal C- and L-Band Observations

open access: yesRemote Sensing, 2019
The planned launch of a spaceborne P-band radar mission and the availability of C- and L-band data from several spaceborne missions suggest investigating the complementarity of C-, L-, and P-band backscatter with respect to the retrieval of forest above ...
Oliver Cartus   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Microwave L-band emission of freezing soil [PDF]

open access: yesIEEE Transactions on Geoscience and Remote Sensing, 2004
We report on field-measured microwave emission in a period of frost penetration into a grassland soil. The measurements were recorded with a high temporal resolution using an L-band radiometer mounted on a 7-m high tower. The observation period (December 2002 to March 2003) included two cycles of soil freezing and thawing with maximum frost depth of 25
Schwank, M.   +5 more
openaire   +4 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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