Results 81 to 90 of about 14,921,642 (304)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

University Symphonic Band, February 11, 1996

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 11, 1996, 3:00 p.m., the 321st concert of the School of Music's 1995-1996 season.University Symphonic Band, Robert L. Spradling, conductor
Western Michigan University. Symphonic Band
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

University Symphonic Band, October 12, 1997

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, October 12, 1997, 3:00 p.m., the 36th concert of the School of Music's 1997-1998 season.University Symphonic Band, Robert L.
Western Michigan University. Symphonic Band
core  

Multipactor suppression in high-power cavity-based L-band low-pass filters by edge geometry optimization

open access: yesФизика волновых процессов и радиотехнические системы
Background. Improving the multipactor resilience of high-power microwave devices used in satellite communication systems presents a primary objective for designers of space technology. Aim.
Ekaterina Yu. Polynova   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

University Symphonic Band, October 27, 1996

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, October 27, 1996, 3:00 p.m., the 90th concert of the School of Music's 1996-1997 season.University Symphonic Band, Robert L. Spradling, conductor ;
Western Michigan University. Symphonic Band
core  

Adaptive Multimodal Fusion of Histopathology and Radiographs for Osteosarcoma Classification Using EfficientNet and Gated Decision Integration

open access: yesIEEE Access
Osteosarcoma diagnosis relies on complementary information from radiographic assessment of bone-level structural abnormalities and histopathological assessment of cellular tissue morphology.
Mehmet Akif Cifci   +6 more
doaj   +1 more source

Improving Sea Ice Characterization in Dry Ice Winter Conditions Using Polarimetric Parameters from C- and L-Band SAR Data

open access: yesRemote Sensing, 2017
Sea ice monitoring and classification is one of the main applications of Synthetic Aperture Radar (SAR) remote sensing. C-band SAR imagery is regarded as an optimal choice for sea ice applications; however, other SAR frequencies has not been extensively ...
Mohammed Dabboor   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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