Results 81 to 90 of about 15,837,467 (256)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

University Concert Band, April 2, 2000

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, April 2, 2000, 3:00 p.m., the 457th concert of the School of Music's 1999-2000 season.University Concert Band, John Lychner, conductor ; Douglas L.
Western Michigan University. Concert Band
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

ParallelCVAE: A Parallel CVAE Mechanism for Multi-Turn Dialog Response Generation Model

open access: yesIEEE Access
Dialog generation in natural language processing, with the goal of generating natural responses based on conversation history, has gained significant attention.
Semih Sevim   +2 more
doaj   +1 more source

University Symphonic Band, February 24, 1974

open access: yes, 2017
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 24, 1974, program no. 155 of the Department of Music’s 1973-1974 season.Western Michigan University Symphonic Band, Carl Bjerregaard ...
Western Michigan University. Symphonic Band
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

University Concert Band, February 12, 1989

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 12, 1989, 3:00 p.m., the 148th concert of the School of Music’s 1988-1989 season.University Concert Band ; Patrick Dunnigan, conductor ...
Western Michigan University. Concert Band
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

University Symphonic Band, October 25, 1998

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, October 25, 1998, 3:00 p.m., the 80th concert of the School of Music's 1998-1999 season.University Symphonic Band, Robert L. Spradling, conductor ;
Western Michigan University. Symphonic Band
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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