Results 71 to 80 of about 15,837,467 (256)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Detecting Arctic Icebergs in Sea Ice in L-Band SAR Images Using a Multiscale CFAR Algorithm

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
This study proposes a multiscale extension of the well-known constant false alarm rate (CFAR) outlier detection method for the detection of icebergs in L-band synthetic aperture radar (SAR) images. The proposed method offers the possibility to accurately
Laust Faerch, Wolfgang Dierking, Nick Hughes, Anthony P. Doulgeris   +3 more
doaj   +1 more source

Decorrelation of L-Band and C-Band Interferometry to volcanic risk prevention [PDF]

, 2013
This work studies correlation of pairs of SAR images focusing on the influence of surface and climate conditions, especially snow coverage and temperature.
D. Sandwell, A. N. TASSETTI, MALINVERNI, Eva Savina, E. S. Malinverni, D. T. SANDWELL, L. CAPPELLETTI   +5 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Multipactor suppression in high-power cavity-based L-band low-pass filters by edge geometry optimization

Физика волновых процессов и радиотехнические системы
Background. Improving the multipactor resilience of high-power microwave devices used in satellite communication systems presents a primary objective for designers of space technology. Aim.
Ekaterina Yu. Polynova, Alexander M. Plotnikov, Alexander P. Semibratov, Alexey S. Yakovlev   +3 more
doaj   +1 more source

A Polarimetric Phased Array Antenna for E-SAR in L-Band [PDF]

, 2006
The design of a new L-band antenna for DLR’s airborne synthetic aperture radar system (E-/F-SAR) is presented. Beside operations in L-band new components for a system upgrade were developed. These components are intro-duced.
Gabler, Bernd, Horn, Ralf, Bachmann, Markus, Limbach, Markus   +3 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Adaptive Multimodal Fusion of Histopathology and Radiographs for Osteosarcoma Classification Using EfficientNet and Gated Decision Integration

IEEE Access
Osteosarcoma diagnosis relies on complementary information from radiographic assessment of bone-level structural abnormalities and histopathological assessment of cellular tissue morphology.
Mehmet Akif Cifci, Aykut Baser, Ibrahim Arpaci, Ali Dogan, Alparslan Guzey, Batuhan Oney, Fazli Yildirim   +6 more
doaj   +1 more source

Improving Sea Ice Characterization in Dry Ice Winter Conditions Using Polarimetric Parameters from C- and L-Band SAR Data

Remote Sensing, 2017
Sea ice monitoring and classification is one of the main applications of Synthetic Aperture Radar (SAR) remote sensing. C-band SAR imagery is regarded as an optimal choice for sea ice applications; however, other SAR frequencies has not been extensively ...
Mohammed Dabboor, Benoit Montpetit, Stephen Howell, Christian Haas   +3 more
doaj   +1 more source