Results 11 to 20 of about 13,341,060 (253)

No H- and L-type cases in Belgium in cattle diagnosed with bovine spongiform encephalopathy (1999-2008) aging seven years and older [PDF]

BMC Veterinary Research, 2010
Background The bovine spongiform encephalopathy (BSE) epidemic presented homogeneity of the phenotype. This classical BSE (called C-type) was probably due to the contamination of the food chain by a single prion strain.
Van Muylem Patrick, Geeroms Riet, Durand Stéphanie, Rodeghiero Caroline, van Keulen Lucien, Langeveld Jan, Dobly Alexandre, De Sloovere Jessica, Vanopdenbosch Emmanuel, Roels Stefan   +9 more
doaj   +2 more sources

Spatial analysis of BSE cases in the Netherlands [PDF]

, 2008
Background In many of the European countries affected by Bovine Spongiform Encephalopathy (BSE), case clustering patterns have been observed. Most of these patterns have been interpreted in terms of heterogeneities in exposure of cattle to the BSE agent.
Thomas J Hagenaars, Heres Lourens, Dick J Brus, Brus Dick J, Brus, D.J., Hagenaars, T.H.J., Heres, L., Lourens Heres, Hagenaars Thomas J   +8 more
core   +1 more source

Radical Change in Zoonotic Abilities of Atypical BSE Prion Strains as Evidenced by Crossing of Sheep Species Barrier in Transgenic Mice

Emerging Infectious Diseases, 2020
Classical bovine spongiform encephalopathy (BSE) is the only zoonotic prion disease described to date. Although the zoonotic potential of atypical BSE prions have been partially studied, an extensive analysis is still needed.
Alba Marín-Moreno, Alvina Huor, Juan Carlos Espinosa, Jean Yves Douet, Patricia Aguilar-Calvo, Naima Aron, Juan Píquer, Sévérine Lugan, Patricia Lorenzo, Cecile Tillier, Hervé Cassard, Olivier Andreoletti, Juan María Torres   +12 more
doaj   +1 more source

Protocol for further laboratory investigations into the distribution of infectivity of Atypical BSE [PDF]

EFSA Journal, 2014
Information on the pathogenesis and tissue distribution of Atypical Bovine Spongiform Encephalopathy (BSE) in cattle through the study of field cases and experimental transmission studies is lacking. The latter are limited to transmission of Atypical BSE
European Food Safety Authority
doaj   +1 more source

Discrimination of Classical and Atypical BSE by a Distinct Immunohistochemical PrP^Sc Profile

Pathogens, 2023
Bovine spongiform encephalopathy (BSE) belongs to the group of transmissible spongiform encephalopathies and is associated with the accumulation of a pathological isoform of the host-encoded glycoprotein, designated prion protein (PrPSc).
Christine Fast, Catherine Graham, Martin Kaatz, Kristina Santiago-Mateo, Tammy Kaatz, Kendra MacPherson, Anne Balkema-Buschmann, Ute Ziegler, Martin H. Groschup, Stefanie Czub   +9 more
doaj   +1 more source

Review on the epidemiology and dynamics of BSE epidemics [PDF]

, 2008
The paper describes how the comprehensive surveillance of bovine spongiform encephalopathy (BSE) and studies carried out on these data has enhanced our knowledge of the epidemiology of BSE.
Ducrot, C., Heim, D., Koeijer, A.A., de, Arnold, M., Calavas, D.   +4 more
core   +1 more source

Evaluation of two sets of immunohistochemical and Western blot confirmatory methods in the detection of typical and atypical BSE cases

BMC Research Notes, 2011
Background Three distinct forms of bovine spongiform encephalopathy (BSE), defined as classical (C-), low (L-) or high (H-) type, have been detected through ongoing active and passive surveillance systems for the disease. The aim of the present study was
Greenlee Justin J, Loiacono Christina M, Hamir Amir N, Acutis Pierluigi, Perazzini Alice Z, Iulini Barbara, Corona Cristiano, Martucci Francesca, Hall S Mark, Porcario Chiara, Richt Jürgen A, Caramelli Maria, Casalone Cristina   +12 more
doaj   +1 more source

Transmissibility of H-Type Bovine Spongiform Encephalopathy to Hamster PrP Transgenic Mice. [PDF]

PLoS ONE, 2015
Two distinct forms of atypical bovine spongiform encephalopathies (H-BSE and L-BSE) can be distinguished from classical (C-) BSE found in cattle based on biochemical signatures of disease-associated prion protein (PrPSc).
Hiroyuki Okada, Kentaro Masujin, Kohtaro Miyazawa, Takashi Yokoyama   +3 more
doaj   +1 more source

Accumulation of L-type Bovine Prions in Peripheral Nerve Tissues

Emerging Infectious Diseases, 2010
We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally ...
Yoshifumi Iwamaru, Morikazu Imamura, Yuichi Matsuura, Kentaro Masujin, Yoshihisa Shimizu, Yujing Shu, Megumi Kurachi, Kazuo Kasai, Yuichi Murayama, Shigeo Fukuda, Sadao Onoe, Ken’ichi Hagiwara, Yoshio Yamakawa, Tetsutaro Sata, Shirou Mohri, Hiroyuki Okada, Takashi Yokoyama   +16 more
doaj   +1 more source

Pruritus is a common feature in sheep infected with the BSE agent. [PDF]

, 2008
BACKGROUND: The variability in the clinical or pathological presentation of transmissible spongiform encephalopathies (TSEs) in sheep, such as scrapie and bovine spongiform encephalopathy (BSE), has been attributed to prion protein genotype, strain ...
Vidal-Diez, Alberto, Chaplin, Melanie J., Simmons, MM, Marion M Simmons, Chaplin, Melani J., Dexter, Glenda, Vidal-Diez, A, Martin Jeffrey, Christine Berthelin-Baker, Bone Gemma, Melanie J Chaplin, Glenda Dexter, Konold Timm, Tortosa Méndez, Raül, Peter Hill, Simmons Marion M, Simmons, Marion M., Tortosa Raul, Chaplin Melanie J, Davis Andrew, Berthelin-Baker, C, Bellworthy, SJ, Dexter Glenda, Bellworthy Susan J, Chaplin, MJ, Susan J Bellworthy, Bellworthy, Susan J., Timm Konold, Hill, P, Berthelin-Baker Christine, Gemma Bone, Raul Tortosa, Tortosa, R, Vidal-Diez Alberto, Jeffrey Martin, Hill, Peter, Konold, T, Hill Peter, Tortosa, Raul, Berthelin-Baker, Christine, Dexter, G, Davis, Andrew, Bone, G, Davis, A, Vidal Díez, Alberto, Jeffrey, M, Bone, Gemma, Jeffrey, Martin, Konold, Timm, Andrew Davis, Alberto Vidal-Diez   +50 more
core   +1 more source