Results 261 to 270 of about 457,288 (287)

L-Cysteine, a Bicarbonate-Sensitive Endogenous Excitotoxin

Science, 1990
After systemic administration to immature rodents, L-cysteine destroys neurons in the cerebral cortex, hippocampus, thalamus, and striatum, but the underlying mechanism has never been clarified. This neurotoxicity of L-cysteine, in vitro or in vivo, has now been shown to be mediated primarily through the N -methyl-D-
J W, Olney, C, Zorumski, M T, Price, J, Labruyere   +3 more
openaire   +2 more sources

Glutamate‐L‐cysteine ligase in breast carcinomas

Histopathology, 2004
Aims : To investigate the immunohistochemical expression of the catalytic and regulatory subunits of γ‐glutamyl cysteine synthetase, i.e. glutamate‐L‐cysteine ligase (GLCL) in 274 invasive and in‐situ breast carcinomas. GLCL is the rate‐limiting enzyme in glutathione synthesis, which is one of the most important intracellular antioxidants participating
Y, Soini, P, Karihtala, A, Mäntyniemi, N, Turunen, P, Pääkkö, V, Kinnula   +5 more
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l-Cysteine Metabolism and Fermentation in Microorganisms

2016
L-Cysteine is an important amino acid both biologically and commercially. Although most amino acids are industrially produced by microbial fermentation, L-cysteine has been mainly produced by protein hydrolysis. Due to environmental and safety problems, synthetic or biotechnological products have been preferred in the market.
Hiroshi, Takagi, Iwao, Ohtsu
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S-(1,2-Dichlorovinyl)-l-Cysteine

2005
S -(1,2-Dichlorovinyl)- l -cysteine (DCVC) (CAS 627-72-5) is a known metabolite of trichloroethylene, which is a common industrial solvent used for degreasing metals. The acute toxicity of DCVC is well characterized in various animal models, including young calves, dogs, cats, rabbits, guinea pigs, turkeys, rats, and mice.
V.S. Vaidya, H.M. Mehendale
openaire   +1 more source

Effect of l-cysteine on acetaldehyde self-administration

Alcohol, 2012
Acetaldehyde (ACD), the first metabolite of ethanol, has been implicated in several behavioural actions of alcohol, including its reinforcing effects. Recently, we reported that l-cysteine, a sequestrating agent of ACD, reduced oral ethanol self-administration and that ACD was orally self-administered.
PEANA, Alessandra Tiziana, Muggironi G, Fois GR, Zinellu M, Sirca D, DIANA, Marco   +5 more
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A Sonogel/L‐Cystein and a SAM L‐Cystein Modified Electrodes for Detection of Dopamine

Macromolecular Symposia, 2008
AbstractSummary: The Sonogel‐Carbon electrode is a special class of sol‐gel electrode that exhibits favourable mechanics and electric properties that can be used as electrochemical sensors. In this study, a Sonogel‐Carbon modified with L‐Cysteine was used to prepare a novel electrochemical sensor. The objective of this new electrode modification was to
H. El Bouhouti, I. Naranjo Rodriguez, J.L. Hidalgo Hidalgo de Cisneros, K. R. Temsamani, M. Choukairi, D. Bouchta   +5 more
openaire   +1 more source

Degradation to Sulphate of S-Methyl-L-Cysteine Sulphoxide and S-Carboxymethyl-L-Cysteine Sulphoxide in Man

Drug Metabolism and Drug Interactions, 2003
A nearly complete recovery of radioactivity was achieved over 14 days following the oral administration of [35S]-S-methyl-L-cysteine sulphoxide and [35S]-S-carboxymethyl-L-cysteine sulphoxide to four healthy male volunteers. The urine was the major pathway of excretion of radioactivity (c. 96% in 0-14 days; c.
Waring, R H, Harris, R M, Steventon, G B, Mitchell, S C   +3 more
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L-Cysteine Oxalates with Dimeric and Trimeric Cations

Journal of Structural Chemistry
Single crystals of two new compounds, (l-CysH···l-Cys)(HC2O4) (I) and (l-CysH···l-Cys···l-CysH)(HC2O4)2·0.5H2O (II), were obtained. Crystal structures were solved and refined using single-crystal X-ray diffraction, and compared with the previously known orthorhombic and monoclinic modifications of the simple salt (l-CysH)(HC2O4).
Ghazaryan, V., Giester, G., Minkov, V., Boldyreva, E., Petrosyan, A.   +4 more
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Synthesis and chromatographic properties of S-(1-carboxyethyl)-L-cysteine and S-(1-carboxypropyl)-L-cysteine.

The Italian journal of biochemistry, 1987
Details are reported for the synthesis of S-(1-carboxyethyl)-L-cysteine (1-CEC) and S-(1-carboxypropyl)-L-cysteine (1-CPC) from cysteine and 2-bromopropionic acid or 2-bromobutyric acid, respectively. Some analytical data and the behaviour of these two compounds on paper and ion-exchange chromatography are also reported, which allow their ...
BLARZINO, Carla, C. Foppoli, COCCIA, Raffaella   +2 more
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Poly-L-cysteine

Journal of the American Chemical Society, 1956
Arieh Berger, Junzo Noguchi, Ephraim Katchalski   +2 more
openaire   +1 more source