Results 1 to 10 of about 695,646 (296)

50 shades of oxidative stress: A state-specific cysteine redox pattern hypothesis

Redox Biology, 2023
Oxidative stress is biochemically complex. Like primary colours, specific reactive oxygen species (ROS) and antioxidant inputs can be mixed to create unique “shades” of oxidative stress.
James N. Cobley
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Interplay between Sulfur Assimilation and Biodesulfurization Activity in Rhodococcus qingshengii IGTS8: Insights into a Regulatory Role of the Reverse Transsulfuration Pathway

mBio, 2022
Biodesulfurization is a process that selectively removes sulfur from dibenzothiophene and its derivatives. Several natural biocatalysts harboring the highly conserved desulfurization operon dszABC, which is significantly repressed by methionine, cysteine,
Olga Martzoukou, Panayiotis D. Glekas, Margaritis Avgeris, Diomi Mamma, Andreas Scorilas, Dimitris Kekos, Sotiris Amillis, Dimitris G. Hatzinikolaou   +7 more
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N-Acetyl-Cysteine: Modulating the Cysteine Redox Proteome in Neurodegenerative Diseases

Antioxidants, 2022
In the last twenty years, significant progress in understanding the pathophysiology of age-associated neurodegenerative diseases has been made. However, the prevention and treatment of these diseases remain without clinically significant therapeutic ...
Marcos Martinez-Banaclocha
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Heparan Sulfate, Mucopolysaccharidosis IIIB and Sulfur Metabolism Disorders

Antioxidants, 2022
Mucopolysaccharidosis, type IIIB (MPS IIIB) is a rare disease caused by mutations in the N-alpha-acetylglucosaminidase (NAGLU) gene resulting in decreased or absent enzyme activity.
Marta Kaczor-Kamińska, Kamil Kamiński, Maria Wróbel   +2 more
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Redox regulation of enzymes involved in sulfate assimilation and in the synthesis of sulfur-containing amino acids and glutathione in plants

Frontiers in Plant Science, 2022
Sulfur is essential in plants because of its presence in numerous molecules including the two amino acids, cysteine, and methionine. Cysteine serves also for the synthesis of glutathione and provides sulfur to many other molecules including protein ...
Linda de Bont, Natacha Donnay, Jérémy Couturier, Jérémy Couturier, Nicolas Rouhier   +4 more
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Label-Free Quantitative Proteomic Analysis of Nitrogen Starvation in Arabidopsis Root Reveals New Aspects of H₂S Signaling by Protein Persulfidation

Antioxidants, 2021
Hydrogen sulfide (H2S)-mediated signaling pathways regulate many physiological and pathophysiological processes in mammalian and plant systems.
Ana Jurado-Flores, Luis C. Romero, Cecilia Gotor   +2 more
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Reaction of Chalcones with Cellular Thiols. The Effect of the 4-Substitution of Chalcones and Protonation State of the Thiols on the Addition Process. Diastereoselective Thiol Addition

Molecules, 2021
Several biological effects of chalcones have been reported to be associated with their thiol reactivity. In vivo, the reactions can result in the formation of small-molecule or protein thiol adducts.
Fatemeh Kenari, Szilárd Molnár, Pál Perjési   +2 more
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Quantification of Intracellular Thiols by HPLC-Fluorescence Detection

Molecules, 2021
Biothiols, such as cysteine and glutathione, play important roles in various intracellular reactions represented by the redox equilibrium against oxidative stress.
Hiroki Yamamoto, Takuya Fujiwara, Takashi Funatsu, Makoto Tsunoda   +3 more
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Neuroprotective Effect of Platinum Nanoparticles Is Not Associated with Their Accumulation in the Brain of Rats

Journal of Functional Biomaterials, 2023
Platinum nanoparticles (nPts) have neuroprotective/antioxidant properties, but the mechanisms of their action in cerebrovascular disease remain unclear.
Alexander Gennadievich Filippov, Valery Vasil’evich Alexandrin, Alexander Vladimirovich Ivanov, Alexander Alexandrovich Paltsyn, Nadezhda Borisovna Sviridkina, Edward Danielevich Virus, Polina Olegovna Bulgakova, Joanna Petrovna Burmiy, Aslan Amirkhanovich Kubatiev   +8 more
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Yohimbine Alleviates Oxidative Stress and Suppresses Aerobic Cysteine Metabolism Elevated in the Rat Liver of High-Fat Diet-Fed Rats

Molecules, 2023
Yohimbine is a small indole alkaloid derived from the bark of the yohimbe tree with documented biological activity, including anti-inflammatory, erectile dysfunction relieving, and fat-burning properties.
Małgorzata Iciek, Magdalena Górny, Magdalena Kotańska, Anna Bilska-Wilkosz, Marta Kaczor-Kamińska, Jacek Zagajewski   +5 more
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