Results 21 to 30 of about 695,646 (296)

Impairments in pyridoxine-dependent sulphur amino acid metabolism are highly sensitive to the degree of vitamin B6 deficiency and repletion in the pig

open access: yesAnimal, 2009
The objectives of the current study included the characterization of the temporal changes in indices of sulphur amino acid metabolism in piglets in response to vitamin B6 deficiency and repletion with graded levels of pyridoxine hydrochloride.
Z. Zhang   +6 more
doaj   +1 more source

A Surface Mediated Supramolecular Chiral Phenomenon for Recognition of l- and d-Cysteine

open access: yesNanomaterials, 2018
Chiral recognition is of fundamental importance in chemistry and life sciences and the principle of chiral recognition is instructive in chiral separation and enantioselective catalysis.
Jing Wang   +4 more
doaj   +1 more source

Family C1 cysteine proteases: Biological diversity or redundancy? [PDF]

open access: yes, 2003
Recent progress in the identification and partial characterization of novel genes encoding cysteine proteases of the papain family has considerably increased our knowledge of this family of enzymes.
Nägler, D. K.   +3 more
core   +1 more source

Discovery of Non-Cysteine-Targeting Covalent Inhibitors by Activity-Based Proteomic Screening with a Cysteine-Reactive Probe

open access: yes, 2022
Covalent inhibitors of enzymes are increasingly appreciated as pharmaceutical seeds, yet discovering non-cysteine-targeting inhibitors remains challenging.
Naotaka Noda   +19 more
core   +1 more source

Potential of Glutathione Antioxidant in the Hippocampus Repair: Preliminary Study on Bioactive Materials Antiaging of Snakehead Fish (Channa striata) in Animal Models of Aging

open access: yesInternational Journal of Science and Engineering, 2015
Snakehead fish meat contains active ingredients with anti-aging potential that serves as a precursor of glutathione. The ability of glutathione as an antiaging opportunities in the utilization of fish meat, especially snakehead fish.
Sunarno Sunarno
doaj   +1 more source

Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis [PDF]

open access: yes, 2012
Recently, mutations in the DNAJC5 gene encoding cysteine-string protein alpha (CSPα) were identified to cause the neurodegenerative disorder adult-onset neuronal ceroid lipofuscinosis.
Greaves, J.   +11 more
core   +1 more source

Sorption performance of cysteine-modified bentonite in heavy metals uptake [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
A local clay, bentonite (N-Ben), was modified by the biologically-based ligand, cysteine (Cys), through a simple sorption technique. The modified sorbent (Cys-Ben) demonstrated affinity for soft and moderately soft heavy metal ions (HMI), such as Cd(II ...
Faghihian Hossein   +1 more
doaj   +1 more source

Instability Mechanism of Osimertinib in Plasma and a Solving Strategy in the Pharmacokinetics Study

open access: yesFrontiers in Pharmacology, 2022
Osimertinib is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) and a star medication used to treat non-small-cell lung carcinomas (NSCLCs).
Zheng Yuan   +10 more
doaj   +1 more source

Impact of glutathione on acute ischemic stroke severity and outcome: possible role of aminothiols redox status

open access: yesRedox Report, 2021
Objective Acute brain ischemia is accompanied by a disruption of low-molecular-weight aminothiols (LMWTs) homeostasis, such as homocysteine (Hcy), cysteine (Cys), and glutathione (GSH).
Marina Yurievna Maksimova   +8 more
doaj   +1 more source

Characterisation of a recombinant human cysteine dioxygenase [PDF]

open access: yes, 2003
Cysteine Dioxygenase is an enzyme that catalyses the reaction of cysteine to cysteinesulfinic acid and is thought to regulate the intracellular concentrations of its substrate.
Barry, Christopher Harper
core   +6 more sources

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