Results 21 to 30 of about 654,528 (315)

Defining and refining the cysteine redoxome with sulfur chemical biology [PDF]

open access: yes, 2022
Posttranslational changes in the redox state of cysteine residues can rapidly and reversibly alter protein function, modulating biological processes and drug pharmacology.
Kate, Carroll
core   +1 more source

Effects of the substitution of amino acid residues, through chemical synthesis, on the conformation and activity of antimicrobial peptides

open access: yesOrbital: The Electronic Journal of Chemistry, 2012
Antimicrobial peptides make up an assorted group of molecules which contain from 12 to 50 amino acid residues and which may be produced by microorganisms, plants and animals.
Regina C. Adão   +4 more
doaj   +1 more source

Enhanced L-cysteine production by overexpressing potential L-cysteine exporter genes in an L-cysteine-producing recombinant strain of Corynebacterium glutamicum [PDF]

open access: yes, 2019
We identified L-cysteine exporter candidates of Corynebacterium glutamicum and investigated the effect of overexpression of the potential L-cysteine exporter genes on L-cysteine production in a recombinant strain of C. glutamicum.
Mayumi Kishino (7351532)   +2 more
core   +1 more source

Biological Mechanisms of S-Nitrosothiol Formation and Degradation: How Is Specificity of S-Nitrosylation Achieved?

open access: yesAntioxidants, 2021
The modification of protein cysteine residues underlies some of the diverse biological functions of nitric oxide (NO) in physiology and disease. The formation of stable nitrosothiols occurs under biologically relevant conditions and time scales. However,
Christopher M. Massa   +8 more
doaj   +1 more source

Palmitoylation-induced aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis [PDF]

open access: yes, 2012
Recently, mutations in the DNAJC5 gene encoding cysteine-string protein alpha (CSPα) were identified to cause the neurodegenerative disorder adult-onset neuronal ceroid lipofuscinosis.
Greaves, J.   +11 more
core   +1 more source

Comparative effects of coconut water and N-Acetyl cysteine on the hypothalamo-pituitary-gonadal axis of male rats [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2017
Coconut water (CW) contains cysteine, an amino acid which influences glutathione metabolism and promotes reproductive functions. The effects of CW and N-acetyl cysteine (NAC) were compared on the hypothalamo-pituitary-gonadal-axis of danazol-(a GnRH ...
Olufadekemi Tolulope Kunle-Alabi   +4 more
doaj   +1 more source

The cysteine proteome

open access: yesFree Radical Biology and Medicine, 2015
The cysteine (Cys) proteome is a major component of the adaptive interface between the genome and the exposome. The thiol moiety of Cys undergoes a range of biologic modifications enabling biological switching of structure and reactivity. These biological modifications include sulfenylation and disulfide formation, formation of higher oxidation states,
Go, Young-Mi   +2 more
openaire   +2 more sources

Cysteine-To-Lysine Transfer Antibody Fragment Conjugation [PDF]

open access: yes, 2019
The modification of lysine residues with acylating agents has represented a ubiquitous approach to the construction of antibody conjugates, with the resulting amide bonds being robustly stable and clinically validated.
Kersti Karu (6953358)   +4 more
core   +3 more sources

Cysteamine bitartrate delayed‐release capsules control leukocyte cystine levels and promote statural growth and kidney health in an open‐label study of treatment‐naïve patients <6 years of age with nephropathic cystinosis

open access: yesJIMD Reports, 2022
Nephropathic cystinosis is a rare autosomal recessive lysosomal storage disease that is characterized by accumulation of cysteine and formation of crystals within cells of different organs and tissues causing systemic manifestations in childhood that ...
Maria Helena Vaisbich   +6 more
doaj   +1 more source

Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors [PDF]

open access: yes, 2019
Acetylcholinesterase cysteine-targeted insecticides against malaria vector Anopheles gambia and other mosquitos have already been introduced. We have applied the olefin metathesis for the preparation of cysteine-targeted insecticides in high yields.
Rudolf Andrys (5988836)   +12 more
core   +1 more source

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