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The role of glutathione transferases in TNT detoxification [PDF]

open access: yes, 2012
Glutathione transferases (GSTs) are multi-functional enzymes with an important role in plant biochemical mechanisms of xenobiotic detoxification. The GSTs have been extensively studied due to their ability to detoxify herbicides; recently they have been ...
Gunning, Vanda
core   +6 more sources

Glutathione [PDF]

open access: yesThe Arabidopsis Book, 2011
Glutathione is a simple sulfur compound composed of three amino acids and the major non-protein thiol in many organisms, including plants. The functions of glutathione are manifold but notably include redox-homeostatic buffering. Glutathione status is modulated by oxidants as well as by nutritional and other factors, and can influence protein structure
Graham, Noctor   +4 more
openaire   +2 more sources

SWADESH: a multimodal multi-disease brain imaging and neuropsychological database and data analytics platform

open access: yesFrontiers in Neurology, 2023
Multimodal neuroimaging data of various brain disorders provides valuable information to understand brain function in health and disease. Various neuroimaging-based databases have been developed that mainly consist of volumetric magnetic resonance ...
Pravat K. Mandal   +16 more
doaj   +1 more source

Glutathione and mitochondria [PDF]

open access: yesFrontiers in Pharmacology, 2014
Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes. While synthesized exclusively in the cytosol from its constituent amino acids, GSH is distributed in different compartments, including ...
Ribas, Vicent   +2 more
openaire   +4 more sources

GLUTATHIONE DETERMINATION AND A STUDY OF THE ACTIVITY OF GLUTATHIONE-PEROXIDASE, GLUTATHIONE-TRANSFERASE, AND GLUTATHIONE-REDUCTASE IN RENAL TRANSPLANTS [PDF]

open access: yesRenal Failure, 2002
The aim of this work is to study the temporary variation of oxidative stress in renal transplants, both in plasma and in erythrocytes (CR). In order to do so, we determined total glutathione (GST) levels, both oxidized (GSSG) and reduced (GSH), and the activity of enzymes, glutathione peroxidase (G-px), glutathione reductase (G-red) and glutathione ...
Vega, L. de   +5 more
openaire   +3 more sources

The Role of Glutathione Transferases in the Detoxification of TNT [PDF]

open access: yes, 2010
Manufacture, use, storage and improper disposal of the explosive 2,4,6-trinitrotoluene (TNT) have led to widespread, global contamination of soil and groundwater.
Sparrow, Helen
core   +6 more sources

Effect of atrazine on glutathione levels, glutathione s-transferase and glutathione reductase activities in pea and wheat plants

open access: yesPlant Protection Science, 2004
Changes were studied in the endogenous level of glutathione (total and oxidised), and in the amount of free thiol groups as caused by the herbicide atrazine on two species of plants with different sensitivity to it.
Lyuba P.-E. Miteva   +3 more
doaj   +1 more source

Intracellular glutathione pools are heterogeneously concentrated [PDF]

open access: yes, 2013
Glutathione is present in millimolar concentrations in the cell, but its relative distribution among cellular compartments remains elusive. We have chosen the endoplasmic reticulum (ER) as an example organelle to study compartment-specific glutathione ...
Christine Tachibana   +8 more
core   +1 more source

Prodrug Approach for Increasing Cellular Glutathione Levels

open access: yesMolecules, 2010
Reduced glutathione (GSH) is the most abundant non-protein thiol in mammalian cells and the preferred substrate for several enzymes in xenobiotic metabolism and antioxidant defense.
Ivana Cacciatore   +4 more
doaj   +1 more source

Plasma glutathione and oxidized glutathione level, glutathione/oxidized glutathione ratio, and albumin concentration in complicated and uncomplicated falciparum malaria

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2016
Objective: To compare the level of glutathione (GSH) and oxidized glutathione (GSSG), the ratio of GSH/GSSG and the concentration of albumin in plasma of patients with complicated and un-complicated falciparum malaria.
Loeki Enggar Fitri   +9 more
doaj   +1 more source

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