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Glutathione is a simple sulfur compound composed of three amino acids and the major non-protein thiol in many organisms, including plants. The functions of glutathione are manifold but notably include redox-homeostatic buffering. Glutathione status is modulated by oxidants as well as by nutritional and other factors, and can influence protein structure
Graham, Noctor +4 more
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Glutathione Transferases [PDF]
The 55 Arabidopsis glutathione transferases (GSTs) are, with one microsomal exception, a monophyletic group of soluble enzymes that can be divided into phi, tau, theta, zeta, lambda, dehydroascorbate reductase (DHAR) and TCHQD classes. The populous phi and tau classes are often highly stress inducible and regularly crop up in proteomic and ...
David P, Dixon, Robert, Edwards
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Fampridine Ameliorates Hepatic Oxidative Stress Caused by Cisplatin in A Rat Model [PDF]
Cisplatin is one of the most potent and commonly used anticancer compounds to treat various tumors, but it causes many unwanted side effects that restrict its use.
Hiewa Dyary, Roz Rashid
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The Response of Thiols to Cadmium Stress in Spinach (Spinacia Oleracea L.)
The aim of this study is to examine the thiol species for the high cadmium (Cd) tolerance of spinach and provide information for the improvement of soil utilization. The spinach was cultured in aqueous solution with concentrations of Cd ranging from 1 to
Ya Gao +4 more
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Effects of inhibiting antioxidant pathways on cellular hydrogen sulfide and polysulfide metabolism [PDF]
Elaborate antioxidant pathways have evolved to minimize the threat of excessive reactive oxygen species (ROS) and to regulate ROS as signaling entities.
Gao, Yan, Olson, Kenneth R.
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Near-infrared (NIR) organic small molecule indocyanine green (ICG) could respond well to 808 nm laser to promote local high temperature and ROS generation for realizing photothermal therapy (PTT)/photodynamic therapy (PDT).
Shu Zhu +5 more
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Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A. +5 more
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The purpose of this work was to study the clinical effectiveness of the application of an advanced method of manufacturing temporary structures and its combination with the applications of hyaluronic acid and the internal administration of quercetin ...
O. V. Voznyi +4 more
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Arabidopsis thaliana dehydroascorbate reductase 2 : conformational flexibility during catalysis [PDF]
Dehydroascorbate reductase (DHAR) catalyzes the glutathione (GSH)-dependent reduction of dehydroascorbate and plays a direct role in regenerating ascorbic acid, an essential plant antioxidant vital for defense against oxidative stress.
Bodra, Nandita +8 more
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Bistable equilibrium points of mercury body burden [PDF]
In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
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