Results 11 to 20 of about 775,294 (358)
Glutathione in the Brain [PDF]
International Journal of Molecular Sciences, 2021 Glutathione (GSH) is the most abundant non-protein thiol, and plays crucial roles in the antioxidant defense system and the maintenance of redox homeostasis in neurons.
K. Aoyama
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Biochimica et Biophysica Acta (BBA) - General Subjects, 2012 BACKGROUND Glutathione (GSH) is present in all mammalian tissues as the most abundant non-protein thiol that defends against oxidative stress. GSH is also a key determinant of redox signaling, vital in detoxification of xenobiotics, regulates cell ...
Shelly C. Lu
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The Arabidopsis Book, 2011 Glutathione is a simple sulfur compound composed of three amino acids and the major non-protein thiol in many organisms, including plants. The functions of glutathione are manifold but notably include redox-homeostatic buffering. Glutathione status is modulated by oxidants as well as by nutritional and other factors, and can influence protein structure
Graham, Noctor +4 more
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Glutathione and mitochondria [PDF]
Frontiers in Pharmacology, 2014 Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes. While synthesized exclusively in the cytosol from its constituent amino acids, GSH is distributed in different compartments, including ...
Ribas, Vicent +2 more
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GLUTATHIONE DETERMINATION AND A STUDY OF THE ACTIVITY OF GLUTATHIONE-PEROXIDASE, GLUTATHIONE-TRANSFERASE, AND GLUTATHIONE-REDUCTASE IN RENAL TRANSPLANTS [PDF]
Renal Failure, 2002 The aim of this work is to study the temporary variation of oxidative stress in renal transplants, both in plasma and in erythrocytes (CR). In order to do so, we determined total glutathione (GST) levels, both oxidized (GSSG) and reduced (GSH), and the activity of enzymes, glutathione peroxidase (G-px), glutathione reductase (G-red) and glutathione ...
Vega, L. de +5 more
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Intracellular glutathione pools are heterogeneously concentrated [PDF]
, 2013 Glutathione is present in millimolar concentrations in the cell, but its relative distribution among cellular compartments remains elusive. We have chosen the endoplasmic reticulum (ER) as an example organelle to study compartment-specific glutathione ...
Christine Tachibana +8 more
core +1 more source
The Response of Thiols to Cadmium Stress in Spinach (Spinacia Oleracea L.)
Toxics, 2022 The aim of this study is to examine the thiol species for the high cadmium (Cd) tolerance of spinach and provide information for the improvement of soil utilization. The spinach was cultured in aqueous solution with concentrations of Cd ranging from 1 to
Ya Gao +4 more
doaj +1 more source
Frontiers in Oncology, 2022 Near-infrared (NIR) organic small molecule indocyanine green (ICG) could respond well to 808 nm laser to promote local high temperature and ROS generation for realizing photothermal therapy (PTT)/photodynamic therapy (PDT).
Shu Zhu +5 more
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Patologìâ, 2019 The purpose of this work was to study the clinical effectiveness of the application of an advanced method of manufacturing temporary structures and its combination with the applications of hyaluronic acid and the internal administration of quercetin ...
O. V. Voznyi +4 more
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Glutathione in Brain Disorders and Aging
Molecules, 2022 Glutathione is a remarkably functional molecule with diverse features, which include being an antioxidant, a regulator of DNA synthesis and repair, a protector of thiol groups in proteins, a stabilizer of cell membranes, and a detoxifier of xenobiotics ...
I. Iskusnykh, A. A. Zakharova, D. Pathak
semanticscholar +1 more source