Results 11 to 20 of about 569,398 (304)
The Arabidopsis Book, 2011 Glutathione is a simple sulfur compound composed of three amino acids and the major non-protein thiol in many organisms, including plants. The functions of glutathione are manifold but notably include redox-homeostatic buffering. Glutathione status is modulated by oxidants as well as by nutritional and other factors, and can influence protein structure
Graham, Noctor +4 more
openaire +2 more sources
The role of glutathione transferases in TNT detoxification [PDF]
, 2012 Glutathione transferases (GSTs) are multi-functional enzymes with an important role in plant biochemical mechanisms of xenobiotic detoxification. The GSTs have been extensively studied due to their ability to detoxify herbicides; recently they have been ...
Gunning, Vanda
core +5 more sources
Glutathione in the Brain [PDF]
International Journal of Molecular Sciences, 2021 Glutathione (GSH) is the most abundant non-protein thiol, and plays crucial roles in the antioxidant defense system and the maintenance of redox homeostasis in neurons. GSH depletion in the brain is a common finding in patients with neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease, and can cause neurodegeneration prior to
openaire +3 more sources
Glutathione and mitochondria [PDF]
Frontiers in Pharmacology, 2014 Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes. While synthesized exclusively in the cytosol from its constituent amino acids, GSH is distributed in different compartments, including ...
Ribas, Vicent +2 more
openaire +4 more sources
GLUTATHIONE DETERMINATION AND A STUDY OF THE ACTIVITY OF GLUTATHIONE-PEROXIDASE, GLUTATHIONE-TRANSFERASE, AND GLUTATHIONE-REDUCTASE IN RENAL TRANSPLANTS [PDF]
Renal Failure, 2002 The aim of this work is to study the temporary variation of oxidative stress in renal transplants, both in plasma and in erythrocytes (CR). In order to do so, we determined total glutathione (GST) levels, both oxidized (GSSG) and reduced (GSH), and the activity of enzymes, glutathione peroxidase (G-px), glutathione reductase (G-red) and glutathione ...
Vega, L. de +5 more
openaire +3 more sources
Intracellular glutathione pools are heterogeneously concentrated [PDF]
, 2013 Glutathione is present in millimolar concentrations in the cell, but its relative distribution among cellular compartments remains elusive. We have chosen the endoplasmic reticulum (ER) as an example organelle to study compartment-specific glutathione ...
Christine Tachibana +12 more
core +1 more source
Effects of inactivity on human muscle glutathione synthesis by a double-tracer and single-biopsy approach [PDF]
, 2010 Oxidative stress is often associated to inactivity-mediated skeletal muscle atrophy. Glutathione is one of the major antioxidant systems stimulated, both at muscular and systemic level, by activation of oxidative processes.
DALLA LIBERA L +29 more
core +1 more source
Erythrocytic Reduced/Oxidized Glutathione and Serum Thiol/Disulfide Homeostasis in Patients with Opioid Use Disorder [PDF]
, 2023 Background: This study aimed to evaluate oxidative damage by measuring erythrocytic reduced/oxidized glutathione as an intracellular thiol pool and serum thiol/disulfide homeostasis as an extracellular thiol pool in patients with opioid use disorder ...
Almila Şenat +10 more
core +1 more source
rebeccalgould/Rqtl2-Kidney-Glutathione: Latest Release
, 2021 Rqtl2 Kidney Glutathione files for QTL ...
Rebecca Lizabeth Gould
core +1 more source
Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast [PDF]
, 2015 Glutathione S-transferase Pi (GST P) has been reported to be a marker of dysplastic lesions. For this reason expression of GST P by intraduct breast carcinoma was evaluated by immunohistochemistry. Thirty-seven of 92 carcinomas (40%) were GST P positive.
Bellamy, C O, Harrison, D J
core +2 more sources