Results 11 to 20 of about 747,792 (297)
50 shades of oxidative stress: A state-specific cysteine redox pattern hypothesis
Redox Biology, 2023 Oxidative stress is biochemically complex. Like primary colours, specific reactive oxygen species (ROS) and antioxidant inputs can be mixed to create unique “shades” of oxidative stress.
James N. Cobley
doaj +1 more source
Nghiên cứu khả năng gắn kết với rotigotine của cluster vàng Au6 bằng lý thuyết phiếm hàm mật độ
Tạp chí Khoa học Đại học Cần Thơ, 2021 Lý thuyết phiếm hàm mật độ (DFT) được sử dụng để khảo sát cơ chế hấp phụ phân tử rotigotine (ROT) lên bề mặt vàng, sử dụng cluster vàng Au6 làm mô hình phản ứng.
Phạm Vũ Nhật +3 more
doaj +1 more source
Redox Biology, 2023 Ferroptosis is inhibited by glutathione peroxidase 4 (GPX4), an antioxidant enzyme that uses reduced glutathione (GSH) as a cofactor to detoxify lipid hydroperoxides. As a selenoprotein, the core function of GPX4 is the thiol-dependent redox reaction. In
Chaoyi Xia +7 more
semanticscholar +1 more source
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis
Nature Cancer, 2022 Aberrant expression of MYC transcription factor family members predicts poor clinical outcome in many human cancers. Oncogenic MYC profoundly alters metabolism and mediates an antioxidant response to maintain redox balance. Here we show that MYCN induces
H. Alborzinia +38 more
semanticscholar +1 more source
Nanomaterials, 2021 The exchange of primary hydrophobic ligands for hydrophilic ones was studied for two types of alloyed AgInS2-ZnS nanocrystals differing in composition and by consequence exhibiting two different emission colors: red (R) and green (G).
Patrycja Kowalik +3 more
doaj +1 more source
Stoichiometric Thiol Redox Proteomics for Quantifying Cellular Responses to Perturbations
Antioxidants, 2021 Post-translational modifications regulate the structure and function of proteins that can result in changes to the activity of different pathways. These include modifications altering the redox state of thiol groups on protein cysteine residues, which ...
Nicholas J. Day +2 more
doaj +1 more source
Cysteine Oxidation in Proteins: Structure, Biophysics, and Simulation
Biochemistry, 2022 Cysteine side chains can exist in distinct oxidation states depending on the pH and redox potential of the environment, and cysteine oxidation plays important yet complex regulatory roles.
Diego Garrido Ruiz +4 more
semanticscholar +1 more source
Plants, 2022 Aluminum (Al) solubilizes into trivalent ions (Al3+) on acidic soils, inhibiting root growth. Since about 13% of global rice cultivation is grown on acidic soils, improving Al tolerance in rice may significantly increase yields.
Lihua Xie +10 more
doaj +1 more source
Bacterial Cysteine-Inducible Cysteine Resistance Systems [PDF]
Journal of Bacteriology, 2016 ABSTRACT Cysteine donates sulfur to macromolecules and occurs naturally in many proteins. Because low concentrations of cysteine are cytotoxic, its intracellular concentration is stringently controlled. In bacteria, cysteine biosynthesis is regulated by feedback inhibition of the activities of serine acetyltransferase (SAT) and 3-
Kazuhiro, Takumi, Gen, Nonaka
openaire +2 more sources
Transsulfuration, minor player or crucial for cysteine homeostasis in cancer.
Trends in Cell Biology, 2022 Cysteine, a thiol-containing amino acid, is crucial for the synthesis of sulfur-containing biomolecules that control multiple essential cellular activities. Altered cysteine metabolism has been linked to numerous driver oncoproteins and tumor suppressors,
Hai‐Feng Zhang +3 more
semanticscholar +1 more source