Results 11 to 20 of about 695,646 (296)
Microbial Cell, 2017 Cysteine is an essential requirement in living organisms. However, due to its reactive thiol side chain, elevated levels of intracellular cysteine can be toxic and therefore need to be rapidly eliminated from the cellular milieu.
Anup Arunrao Deshpande +3 more
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Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB [PDF]
, 2013 Cysteine proteases of the papain superfamily are present in nearly all eukaryotes. They play pivotal roles in the biology of parasites and inhibition of cysteine proteases is emerging as an important strategy to combat parasitic diseases such as sleeping
Mottram, Jeremy C +5 more
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Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]
, 2013 Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F. +11 more
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Characterisation of the yeast Nfs1/Isd11 cysteine desulphurase complex [PDF]
, 2010 PhDSmall inorganic assemblies of alternating ferrous/ferric iron and sulphide ions, so-called iron–sulphur (Fe–S) clusters, are probably nature‟s most ancient prosthetic groups.
Terali, Kerem
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Bacterial Cysteine-Inducible Cysteine Resistance Systems [PDF]
Journal of Bacteriology, 2016 ABSTRACT Cysteine donates sulfur to macromolecules and occurs naturally in many proteins. Because low concentrations of cysteine are cytotoxic, its intracellular concentration is stringently controlled. In bacteria, cysteine biosynthesis is regulated by feedback inhibition of the activities of serine acetyltransferase (SAT) and 3-
Kazuhiro, Takumi, Gen, Nonaka
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mBio, 2023 Many bacteria of the genus Shewanella are facultative anaerobes able to reduce a broad range of soluble and insoluble substrates, including Fe(III) mineral oxides.
Michael P. Norman +8 more
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Biomolecules, 2020 Gluten protein crosslinking is a predetermined process where specific intra- and intermolecular disulfide bonds differ depending on the protein and cysteine motif. In this article, all-atom Monte Carlo simulations were used to understand the formation of
Joel Markgren +4 more
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Free Radical Biology and Medicine, 2015 The cysteine (Cys) proteome is a major component of the adaptive interface between the genome and the exposome. The thiol moiety of Cys undergoes a range of biologic modifications enabling biological switching of structure and reactivity. These biological modifications include sulfenylation and disulfide formation, formation of higher oxidation states,
Go, Young-Mi +2 more
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Oxidants, Antioxidants and Thiol Redox Switches in the Control of Regulated Cell Death Pathways
Antioxidants, 2020 It is well appreciated that biological reactive oxygen and nitrogen species such as hydrogen peroxide, superoxide and nitric oxide, as well as endogenous antioxidant systems, are important modulators of cell survival and death in diverse organisms and ...
Moran Benhar
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Nanocomposites, 2019 l-Cysteine-modified dendritic fibrous nanosilica grafted by amine groups (Cys-DFNS-NH2) have been synthesized by a novel hydrothermal method. The N2 adsorption–desorption isotherms analysis on the Cys-DFNS-NH2 show that the average pore volume and ...
Nilufar Khantan +2 more
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