Cysteine-independent activation/inhibition of heme oxygenase-2 [PDF]
Figure 1: Menadione activation of recombinant FL-hHO-2 (open circles) was similar to the same enzyme without thiols-FL-hHO-2 Cys265,282-Ala (closed triangles).Figure 2: QC-2350 inhibition of recombinant and microsomal HO-2.
Kanji Nakatsu (2809330)
core +1 more source
Vortex Fluidic Mediated Oxidative Sulfitolysis of Oxytocin
In peptide production, oxidative sulfitolysis can be used to protect the cysteine residues during purification, and the introduction of a negative charge aids solubility. Subsequent controlled reduction aids in ensuring correct disulfide bridging.
Emily M. Crawley +3 more
doaj +1 more source
Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones [PDF]
Histone ubiquitination affects the structure and function of nucleosomes through tightly regulated dynamic reversible processes. The efficient preparation of ubiquitinated histones and their analogs is important for biochemical and biophysical studies on
Ze-Bin Tong (6330731) +16 more
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Molecular Docking Studies of N-Acetyl Cysteine, Zinc Acetyl Cysteine and Niclosamide on SARS Cov 2 Protease and Its Comparison with Hydroxychloroquine [PDF]
To Respected Sir/Madam Chemarxiv Respected Sir/Madam Sub: submission of preprint of article to Chemarxiv for online publication. I am herewith submitting the preprint of an article entitled “Molecular docking studies of N-acetyl cysteine,
Roopa Guthappa (8738343) +1 more
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Cysteine-Rich Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor [PDF]
α-Conotoxins that target muscle nicotinic acetylcholine receptors (nAChRs) commonly fall into two structural classes, frameworks I and II containing two and three disulfide bonds, respectively.
Zoltan Dekan +23 more
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Is Development of High-Grade Gliomas Sulfur-Dependent?
We characterized γ-cystathionase, rhodanese and 3-mercaptopyruvate sulfurtransferase activities in various regions of human brain (the cortex, thalamus, hypothalamus, hippocampus, cerebellum and subcortical nuclei) and human gliomas with II to IV grade ...
Maria Wróbel +5 more
doaj +1 more source
Benchmarking in silico Tools for Cysteine pKa Prediction [PDF]
Accurate estimation of the pKas of cysteine residues in proteins could inform targeted approaches in hit discovery. The pKa of a targetable cysteine residue in a disease-related protein is an important physiochemical parameter in covalent drug dis ...
Andrei, Golosov +2 more
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The fermentation of synthesis gas, or syngas, by acetogenic bacteria can help in transitioning from a fossil-fuel-based to a renewable bioeconomy. The main fermentation products of Clostridium ljungdahlii, one of such microorganisms, are acetate and ...
Alba Infantes +2 more
doaj +1 more source
Viral cysteine proteinases [PDF]
Dozens of novel cysteine proteinases have been identified in positive single-stranded RNA viruses and, for the first time, in large double-stranded DNA viruses. The majority of these proteins are distantly related to papain or chymotrypsin and may be direct descendants of primordial proteolytic enzymes.
Gorbalenya, Alexander E. +1 more
openaire +2 more sources
Simple synthesis of ZnO nanoparticles on N-doped reduced graphene oxide for the electrocatalytic sensing of L-cysteine [PDF]
A new kind of ZnO nanoparticle/N-doped reduced graphene oxide nanocomposite (ZnONPs/N-rGO) was synthesized through a low temperature, low-cost and one step hydrothermal process.
Guifang Wang (419763) +4 more
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