Results 41 to 50 of about 654,528 (315)

Cysteine-independent activation/inhibition of heme oxygenase-2 [PDF]

open access: yes, 2016
Figure 1: Menadione activation of recombinant FL-hHO-2 (open circles) was similar to the same enzyme without thiols-FL-hHO-2 Cys265,282-Ala (closed triangles).Figure 2: QC-2350 inhibition of recombinant and microsomal HO-2.
Kanji Nakatsu (2809330)
core   +1 more source

Vortex Fluidic Mediated Oxidative Sulfitolysis of Oxytocin

open access: yesMolecules, 2022
In peptide production, oxidative sulfitolysis can be used to protect the cysteine residues during purification, and the introduction of a negative charge aids solubility. Subsequent controlled reduction aids in ensuring correct disulfide bridging.
Emily M. Crawley   +3 more
doaj   +1 more source

Cysteine-Aminoethylation-Assisted Chemical Ubiquitination of Recombinant Histones [PDF]

open access: yes, 2019
Histone ubiquitination affects the structure and function of nucleosomes through tightly regulated dynamic reversible processes. The efficient preparation of ubiquitinated histones and their analogs is important for biochemical and biophysical studies on
Ze-Bin Tong (6330731)   +16 more
core   +1 more source

Molecular Docking Studies of N-Acetyl Cysteine, Zinc Acetyl Cysteine and Niclosamide on SARS Cov 2 Protease and Its Comparison with Hydroxychloroquine [PDF]

open access: yes, 2020
To Respected Sir/Madam Chemarxiv Respected Sir/Madam Sub: submission of preprint of article to Chemarxiv for online publication. I am herewith submitting the preprint of an article entitled “Molecular docking studies of N-acetyl cysteine,
Roopa Guthappa (8738343)   +1 more
core   +1 more source

Cysteine-Rich Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor [PDF]

open access: yes, 2022
α-Conotoxins that target muscle nicotinic acetylcholine receptors (nAChRs) commonly fall into two structural classes, frameworks I and II containing two and three disulfide bonds, respectively.
Zoltan Dekan   +23 more
core   +1 more source

Is Development of High-Grade Gliomas Sulfur-Dependent?

open access: yesMolecules, 2014
We characterized γ-cystathionase, rhodanese and 3-mercaptopyruvate sulfurtransferase activities in various regions of human brain (the cortex, thalamus, hypothalamus, hippocampus, cerebellum and subcortical nuclei) and human gliomas with II to IV grade ...
Maria Wróbel   +5 more
doaj   +1 more source

Benchmarking in silico Tools for Cysteine pKa Prediction [PDF]

open access: yes, 2023
Accurate estimation of the pKas of cysteine residues in proteins could inform targeted approaches in hit discovery. The pKa of a targetable cysteine residue in a disease-related protein is an important physiochemical parameter in covalent drug dis ...
Andrei, Golosov   +2 more
core   +1 more source

Evaluation of Media Components and Process Parameters in a Sensitive and Robust Fed-Batch Syngas Fermentation System with Clostridium ljungdahlii

open access: yesFermentation, 2020
The fermentation of synthesis gas, or syngas, by acetogenic bacteria can help in transitioning from a fossil-fuel-based to a renewable bioeconomy. The main fermentation products of Clostridium ljungdahlii, one of such microorganisms, are acetate and ...
Alba Infantes   +2 more
doaj   +1 more source

Viral cysteine proteinases [PDF]

open access: yesPerspectives in Drug Discovery and Design, 1996
Dozens of novel cysteine proteinases have been identified in positive single-stranded RNA viruses and, for the first time, in large double-stranded DNA viruses. The majority of these proteins are distantly related to papain or chymotrypsin and may be direct descendants of primordial proteolytic enzymes.
Gorbalenya, Alexander E.   +1 more
openaire   +2 more sources

Simple synthesis of ZnO nanoparticles on N-doped reduced graphene oxide for the electrocatalytic sensing of L-cysteine [PDF]

open access: yes, 1900
A new kind of ZnO nanoparticle/N-doped reduced graphene oxide nanocomposite (ZnONPs/N-rGO) was synthesized through a low temperature, low-cost and one step hydrothermal process.
Guifang Wang (419763)   +4 more
core   +1 more source

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