Results 61 to 70 of about 917,448 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Study of Bioactivity and Physicochemical Properties of New Metal Chelates of Schiff Base Derived from 4-Aminoantipyrine with Cysteine

Indonesian Journal of Chemistry
Transition metallic complexes Cr, Co, Ni, Mn, and Cu were designed and prepared using a new bidentate chelator ligand from 4-aminoantipyrine with cysteine.
Kawther Adeeb Hussein, Dina Naseer Ali, Marwa Faeq   +2 more
doaj   +1 more source

Protein Redox State Monitoring Studies of Thiol Reactivity

Antioxidants, 2019
Protein cysteine thiol status is a major determinant of oxidative stress and oxidant signaling. The -SulfoBiotics- Protein Redox State Monitoring Kit provides a unique opportunity to investigate protein thiol states.
Yuichiro J. Suzuki, Lucia Marcocci, Takashi Shimomura, Yuki Tatenaka, Yuya Ohuchi, Tinatin I. Brelidze   +5 more
doaj   +1 more source

Combination of Cysteine and Glutathione Prevents Ethanol-Induced Hangover and Liver Damage by Modulation of Nrf2 Signaling in HepG2 Cells and Mice

Antioxidants, 2023
Excessive alcohol consumption increases oxidative stress, leading to alcoholic liver disease. In this study, the protective effects of a mixture of cysteine and glutathione against ethanol-induced hangover and liver damage were evaluated in mice and ...
Hyeongyeong Kim, Hyung Joo Suh, Ki-Bae Hong, Eun-Jin Jung, Yejin Ahn   +4 more
doaj   +1 more source

Precise Molecular Structures of Cysteine, Cystine, Hydrogen-Bonded Dicysteine, Cysteine Dipeptide, Glutathione and Acetyl Cysteine Based on Additivity of Atomic Radii [PDF]

, 2011
Structures of molecules are usually represented by arbitrary line drawings, ball and stick or space filling models. In recent years, the author found that using the appropriate radii of atoms and ions, bond lengths in inorganic, organic and biomolecules ...
Raji Heyrovska
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Redox State of Glutathione and Cysteine in Plasma Following Acute Stroke

Antioxidants
Ischemic stroke is a major cause of long-term disability and death, with oxidative stress contributing substantially to post-ischemic injury. Reperfusion restores oxygen supply but simultaneously increases reactive oxygen species (ROS), amplifying ...
Christopher McGinley, Oyinkansola Adeyemi, Oluwafayokemi Oyolola, Byron D. Ford, Gregory D. Ford   +4 more
doaj   +1 more source

Floret Biofortification of Broccoli Using Amino Acids Coupled with Selenium under Different Surfactants: A Case Study of Cultivating Functional Foods

Plants, 2023
Broccoli serves as a functional food because it can accumulate selenium (Se), well-known bioactive amino-acid-derived secondary metabolites, and polyphenols.
Dimitris L. Bouranis, Georgios P. Stylianidis, Vassiliki Manta, Evangelos N. Karousis, Andriani Tzanaki, Despina Dimitriadi, Emmanuel A. Bouzas, Vassilis F. Siyiannis, Violetta Constantinou-Kokotou, Styliani N. Chorianopoulou, Elke Bloem   +10 more
doaj   +1 more source

Simultaneous cyclization and derivatization of peptides using cyclopentenediones [PDF]

, 2017
Unprotected linear peptides containing N-terminal cysteines and another cysteine residue can be simultaneously cyclized and derivatized using 2,2-disubstituted cyclopentenediones. High yields of cyclic peptide conjugates may be obtained in short reaction
Agramunt, Jordi, Archibald, Lewis J., Brun, Omar, Grandas, Anna, Pedroso, Enrique   +4 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source