Results 1 to 10 of about 47,507 (264)
eLife, 2021 The mechanistic target of rapamycin complex 1 (mTORC1) stimulates a coordinated anabolic program in response to growth-promoting signals. Paradoxically, recent studies indicate that mTORC1 can activate the transcription factor ATF4 through mechanisms ...
Margaret E Torrence +6 more
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Frontiers in Physiology, 2022 The plasma membrane transporter xCT belongs to the SLC7 family and has the physiological role of mediating the exchange of glutamate and cystine across the cell plasma membrane, being crucial for redox control.
Michele Galluccio +9 more
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Genetic Landscape of Nephropathic Cystinosis in Russian Children
Frontiers in Genetics, 2022 Nephropathic cystinosis is a rare autosomal recessive disorder characterized by amino acid cystine accumulation and caused by biallelic mutations in the CTNS gene.
K. V. Savostyanov +12 more
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Frontiers in Cell and Developmental Biology, 2021 Among gynecologic malignancies, ovarian cancer is the third most prevalent and the most common cause of death, especially due to diagnosis at an advanced stage together with resistance to therapy.
Sofia C. Nunes +16 more
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Frontiers in Chemistry, 2020 Disulfide bridges establish a fundamental element in the molecular architecture of proteins and peptides which are involved e.g., in basic biological processes or acting as toxins. NMR spectroscopy is one method to characterize the structure of bioactive
Christoph Wiedemann +3 more
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Life, 2022 The plant Saussurea costus (Falc) Lipsch has many biological activities and a strong curative and preventive power against a variety of diseases including cancer, diabetes, and hemorrhoids. In the current study, phytochemical screening was carried out as
Naima Mammate +8 more
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Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli. [PDF]
PLoS ONE, 2015 Intracellular thiols like L-cystine and L-cystine play a critical role in the regulation of cellular processes. Here we show that Escherichia coli has two L-cystine transporters, the symporter YdjN and the ATP-binding cassette importer FliY-YecSC.
Iwao Ohtsu +7 more
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Chronic Sulfasalazine Treatment in Mice Induces System xc− - Independent Adverse Effects
Frontiers in Pharmacology, 2021 Despite ample evidence for the therapeutic potential of inhibition of the cystine/glutamate antiporter system xc− in neurological disorders and in cancer, none of the proposed inhibitors is selective. In this context, a lot of research has been performed
Lise Verbruggen +10 more
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Role of Dual Energy CT Scan in Evaluation of the Chemical Composition of Renal Stones [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: For appropriate management of renal stone knowing its composition is important. Laboratory chemical analysis of the stones involves sophisticated techniques.
Sachin Khanduri +7 more
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The content of non-essential amino acids in the grains of winter and spring varieties of oats (Avena sativa L.) under the conditions of Central Southern Bulgaria [PDF]
Agroznanje, 2013 The purpose of this survey is to study the content of non-essential amino acids in four winter (Dunav 1, Ruse 8, Resor 1, Line M-K) and five spring (Obraztsov chiflik 4, Mina, HiFi, Novosadski golozarnest and Prista 2) cultivars of oats grown in Central ...
Georgieva T., Zorovski P.
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