Results 21 to 30 of about 47,507 (264)

Quantitative determination of D4-cystine in mice using LC-MS/MS and its application to the assessment of pharmacokinetics and bioavailability

Journal of Pharmaceutical Analysis, 2021
Cystine is the primary source material for the synthesis of glutathione. However, the pharmacokinetics and tissue distribution of cystine are largely unknown.
Shuning Li, Zhenyao Lu, Li Jiao, Ran Zhang, Yu Hong, Jiye Aa, Guangji Wang   +6 more
doaj   +1 more source

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells

Cell Reports, 2018
How cancer cells respond to nutrient deprivation remains poorly understood. In certain cancer cells, deprivation of cystine induces a non-apoptotic, iron-dependent form of cell death termed ferroptosis.
Amy Tarangelo, Leslie Magtanong, Kathryn T. Bieging-Rolett, Yang Li, Jiangbin Ye, Laura D. Attardi, Scott J. Dixon   +6 more
doaj   +1 more source

Contents of Urinary System Stones in North Marmara Region and Their Distribution by Gender

Journal of Urological Surgery, 2020
Objective:We aimed to determine the contents of kidney stones in our country by evaluating the results of the stone analysis of patients who underwent surgery due to ureteral or kidney stones or experienced spontaneous stone expulsion.Materials and ...
Ekrem Güner, Kamil Gökhan Şeker
doaj   +1 more source

Urolithiasis in dogs: Evaluation of trends in urolith composition and risk factors (2006‐2018)

Journal of Veterinary Internal Medicine, 2021
Background Urolithiasis is a common and often recurrent problem in dogs. Objective To evaluate trends in urolith composition in dogs and to assess risk factors for urolithiasis, including age, breed, sex, neuter status, urolith location, and bacterial ...
Lucy Kopecny, Carrie A. Palm, Gilad Segev, Jodi L. Westropp   +3 more
doaj   +1 more source

Low‐Level Arsenic Removal from Drinking Water

Global Challenges, 2019
The reported ability of cysteine and cystine to bind typical arsenic oxy‐ions in water is used as a basis for a study of the potential for using a surfactant with a cysteine head‐group for selective arsenic binding and removal in an ion flotation process.
Fatemeh Makavipour, Richard M. Pashley, A. F. M. Mokhlesur Rahman   +2 more
doaj   +1 more source

Epidemiological Evaluation of Neuter Status, Sex, and Breed in Dogs With Cystine Uroliths

Journal of Veterinary Internal Medicine
Background The majority of cystine uroliths occur in intact male dogs. Androgen‐dependent (Type III) cystinuria is considered the most common cause. Objectives Identify dog breeds in which castration is likely to decrease the risk of cystine uroliths ...
Jody P. Lulich, Rachael Ulrich, Eva Furrow   +2 more
doaj   +1 more source

The relationship between structural lipids of sheep wool with its individual macrostructural components, chemical composition and physical indicators

Біологія тварин, 2021
The data on the peculiarities of the structural organization, chemical composition and physical parameters of sheep wool of different breeds depending on the type of their hair are presented.
P. V. Stapay, N. P. Stakhiv, V. M. Tkachuk, O. O. Smolianinova   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Inducing disulfidptosis in tumors:potential pathways and significance

MedComm
Regulated cell death (RCD) is crucial for the elimination of abnormal cells. In recent years, strategies aimed at inducing RCD, particularly apoptosis, have become increasingly important in cancer therapy.
Tao Mi, Xiangpan Kong, Meiling Chen, Peng Guo, Dawei He   +4 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source