Results 11 to 20 of about 55,240 (308)

Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli. [PDF]

open access: yesPLoS ONE, 2015
Intracellular thiols like L-cystine and L-cystine play a critical role in the regulation of cellular processes. Here we show that Escherichia coli has two L-cystine transporters, the symporter YdjN and the ATP-binding cassette importer FliY-YecSC.
Iwao Ohtsu   +7 more
doaj   +2 more sources

Disruption of a cystine transporter downregulates expression of genes involved in sulfur regulation and cellular respiration [PDF]

open access: yesBiology Open, 2016
Cystine and cysteine are important molecules for pathways such as redox signaling and regulation, and thus identifying cellular deficits upon deletion of the Saccharomyces cerevisiae cystine transporter Ers1p allows for a further understanding of cystine
Jessica A. Simpkins   +10 more
doaj   +2 more sources

Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming

open access: yesFrontiers in Cell and Developmental Biology, 2021
Among gynecologic malignancies, ovarian cancer is the third most prevalent and the most common cause of death, especially due to diagnosis at an advanced stage together with resistance to therapy.
Sofia C. Nunes   +16 more
doaj   +1 more source

The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells

open access: yesAntioxidants, 2018
Cystinosin is a lysosomal transmembrane protein which facilitates transport of the disulphide amino acid cystine (CySS) from the lysosomes of the cell.
Rodolfo Sumayao   +2 more
doaj   +1 more source

Intracellular Distribution of Cystine in Cystine-Loaded Proximal Tubules [PDF]

open access: yesPediatric Research, 1994
Cellular cystine loading with cystine dimethyl ester has been shown to inhibit transport in proximal convoluted tubules perfused in vitro and decrease the rate of oxygen consumption in suspensions of proximal tubules. The present study was designed to examine the intracellular distribution of cystine in this model of the Fanconi syndrome of cystinosis ...
A, Sakarcan, C, Timmons, M, Baum
openaire   +2 more sources

Accurate Molecular Weight Measurements of Cystine Derivatives on FAB-MS [PDF]

open access: yes, 2023
Cystine derivatives are important biomolecules in living systems. In this study, the accurate molecular weights of various cysteines and S-S bond-containing peptides were obtained by mass spectrometry using a dithiodiethanol (DTDE) matrix and fast atom ...
藤嶽, 美穂代   +9 more
core  

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

open access: yeseLife, 2017
Many mammalian cancer cell lines depend on glutamine as a major tri-carboxylic acid (TCA) cycle anaplerotic substrate to support proliferation. However, some cell lines that depend on glutamine anaplerosis in culture rely less on glutamine catabolism to ...
Alexander Muir   +5 more
doaj   +1 more source

Cysteines and Disulfide Bonds as Structure-Forming Units: Insights From Different Domains of Life and the Potential for Characterization by NMR

open access: yesFrontiers in Chemistry, 2020
Disulfide bridges establish a fundamental element in the molecular architecture of proteins and peptides which are involved e.g., in basic biological processes or acting as toxins. NMR spectroscopy is one method to characterize the structure of bioactive
Christoph Wiedemann   +3 more
doaj   +1 more source

Níveis de aminoácidos na dieta de suínos machos inteiros dos 25 aos 70KG Levels of aminoacids in diet for boars from 25 at 70KG

open access: yesCiência Rural, 1999
No Brasil, o abate de suínos machos inteiros é proibido, mas esta categoria apresenta vantagens econômicas quando comparada a suínos machos castrados. Trabalhos têm demonstrado que existem diferenças no requerimento nutricional entre essas categorias.
Cezar Dobler Castagna   +3 more
doaj   +1 more source

Antioxidant and Anti-Urolithiatic Activity of Aqueous and Ethanolic Extracts from Saussurea costus (Falc) Lispich Using Scanning Electron Microscopy

open access: yesLife, 2022
The plant Saussurea costus (Falc) Lipsch has many biological activities and a strong curative and preventive power against a variety of diseases including cancer, diabetes, and hemorrhoids. In the current study, phytochemical screening was carried out as
Naima Mammate   +8 more
doaj   +1 more source

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