Results 31 to 40 of about 55,240 (308)

Impact of ribosomal protein uL3 status on cystine/glutamate antiporter xCT expression

, 2023
The human ribosomal protein L3 (uL3) has been identified as a key sensor in the cell response to chemotherapeutic drugs in colorectal cancer (CRC) cells lacking active p53.
Giulia Russo, Annalisa Pecoraro, Chiara Brignola, Annapina Russo, Camilla Danisi   +4 more
core  

Epidemiological Evaluation of Neuter Status, Sex, and Breed in Dogs With Cystine Uroliths

Journal of Veterinary Internal Medicine
Background The majority of cystine uroliths occur in intact male dogs. Androgen‐dependent (Type III) cystinuria is considered the most common cause. Objectives Identify dog breeds in which castration is likely to decrease the risk of cystine uroliths ...
Jody P. Lulich, Rachael Ulrich, Eva Furrow   +2 more
doaj   +1 more source

The relationship between structural lipids of sheep wool with its individual macrostructural components, chemical composition and physical indicators

Біологія тварин, 2021
The data on the peculiarities of the structural organization, chemical composition and physical parameters of sheep wool of different breeds depending on the type of their hair are presented.
P. V. Stapay, N. P. Stakhiv, V. M. Tkachuk, O. O. Smolianinova   +3 more
doaj   +1 more source

Cystine-based MBioF for Maintaining the Antioxidant–Oxidant Balance in Airway Diseases

, 2018
Reactive oxygen species, contributing to oxidant–antioxidant imbalance, initiate damage to the airways cells, inflammatory processes, and further pathophysiological effects.
Artur P. Terzyk, Pilar Ferrer, Marek Wiśniewski (1542589), Paulina Bolibok, Adam Bieniek (6008714), Pilar Ferrer (6008717), Katarzyna Roszek (5333948), Artur P. Terzyk (1364586), Adam Bieniek, Joanna Czarnecka, Ivan da Silva, Marek Wiśniewski, Joanna Czarnecka (630019), Ivan da Silva (2878130), Katarzyna Roszek, Paulina Bolibok (5333951)   +15 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Hyperosmolarity induced cystine transport and cystine cysteine cycle between erythrocytes and the plasma

, 2008
The objective of the present study was to determine if a cystine-cysteine cycle operates between the erythrocytes and the plasma. In the present study we incubated the erythrocytes in krebs ringer phosphate buffer with different osmolarity containing ...
Yıldız D, Çakır Sahilli Y.
core   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

FANCONI SYNDROME SECONDARY TO CYSTINOSIS IN YOUNG MALE: A CASE REPORT

Khyber Medical University Journal, 2021
INTRODUCTION:  Nephropathic cystinosis is a rarely occurring inherited metabolic disorder, leading to Fanconi syndrome, progressive renal failure and a range of extra-renal manifestations including endocrinopathies.
Samina Bibi, Mian Sameer Ahmed, Bakht Babar, Tahir Ghaffar, Azizul Hassan Aamir, Sana Aziz   +5 more
doaj   +1 more source

CCD Charge Density Study on Crystals with Large Unit Cell Parameters: The Case of Hexagonal l-Cystine

, 2016
The electron density of l-cystine has been analyzed using 110 K single-crystal Mo Kα X-ray diffraction data to a resolution of (sin θ/λ)max = 1.123 Å-1 with a CCD area detector. Due to the large c-parameter (55.9 Å), a discussion is made for choosing the
C. Lecomte (2008081), J. A. K. Howard (1755409), S. Dahaoui (2963739), V. Pichon-Pesme (3054393)   +3 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source