Results 31 to 40 of about 695,646 (296)

Enrichment of Cysteine-Containing Peptide by On-Resin Capturing and Fixed Charge Tag Derivatization for Sensitive ESI-MS Detection

Molecules, 2020
High complexity of cell and tissue proteomes limits the investigation of proteomic biomarkers. Therefore, the methods of enrichment of some chemical groups of peptides including thiopeptides are important tools that may facilitate the proteomic analysis ...
Remigiusz Bąchor, Oliwia Gorzeń, Anna Rola, Karolina Mojsa, Karolina Panek-Laszczyńska, Andrzej Konieczny, Krystyna Dąbrowska, Wojciech Witkiewicz, Zbigniew Szewczuk   +8 more
doaj   +1 more source

Exploring the Antioxidant Roles of Cysteine and Selenocysteine in Cellular Aging and Redox Regulation

Biomolecules
Aging is a complex, universal biological process characterized by the progressive and irreversible decline of physiological functions across multiple organ systems.
Marta Pace, Chiara Giorgi, Giorgia Lombardozzi, Annamaria Cimini, Vanessa Castelli, Michele d’Angelo   +5 more
doaj   +1 more source

A Novel Fluorescence Probe Based on Azamonardine for Detecting and Imaging Cysteine in Cells and Zebrafish with High Selectivity and Sensitivity

Molecules, 2023
A novel fluorescent probe based on azamonardine (Aza) fluorophore was designed and synthesized for the highly selective detection of cysteine (Cys) in vivo and in vitro.
Yixu Zhao, Ting Wang, Ahmed Mohammed Ali Abdulkhaleq, Zhongfu Zuo, Yongjin Peng, Xibin Zhou   +5 more
doaj   +1 more source

Fragmentation of protonated ions of peptides containing cysteine, cysteine sulfinic acid, and cysteine sulfonic acid [PDF]

Journal of the American Society for Mass Spectrometry, 2004
The oxidation of the sulfhydryl group in cysteine to sulfenic acid, sulfinic acid, and sulfonic acid in proteins is important in a number of enzymatic processes. In this study we examined the fragmentation of four peptides containing cysteine, cysteine sulfinic acid (Cys-SO(2)H), and cysteine sulfonic acid (Cys-SO(3)H) in an ion-trap mass spectrometer.
Wang, Yinsheng, Vivekananda, Shetty, Men, Lijie, Zhang, Qibin   +3 more
openaire   +2 more sources

Gold Nanoparticles-Based Colorimetric Immunoassay of Carcinoembryonic Antigen with Metal–Organic Framework to Load Quinones for Catalytic Oxidation of Cysteine

Sensors
This work reported gold nanoparticles (AuNPs)-based colorimetric immunoassay with the Cu-based metal–organic framework (MOF) to load pyrroloquinoline quinone (PQQ) for the catalytic oxidation of cysteine.
Zhao-Jiang Yu, Ting-Ting Yang, Gang Liu, De-Hua Deng, Lin Liu   +4 more
doaj   +1 more source

The Highly Conservative Cysteine of Oncomodulin as a Feasible Redox Sensor

Biomolecules, 2021
Oncomodulin (Ocm), or parvalbumin β, is an 11–12 kDa Ca2+-binding protein found inside and outside of vertebrate cells, which regulates numerous processes via poorly understood mechanisms.
Alisa A. Vologzhannikova, Polina A. Khorn, Marina P. Shevelyova, Alexei S. Kazakov, Victor I. Emelyanenko, Eugene A. Permyakov, Sergei E. Permyakov   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

New Insight into Mercury Removal from Fish Meat Using a Single‐Component Solution Containing cysteine

Global Challenges
A novel approach for reducing mercury content in fish meat during post‐packaging storage is developed to extend the margin of their safe consumption.
Przemysław Strachowski, Geeta Mandava, Johan Lundqvist, Romain Bordes, Mehdi Abdollahi   +4 more
doaj   +1 more source

A Near-Infrared Ratiometric Fluorescent Probe for Highly Selective Recognition and Bioimaging of Cysteine

Frontiers in Chemistry, 2019
A benzothiazole-based near-infrared (NIR) ratiometric fluorescent probe (HBT-Cys) was developed for discriminating cysteine (Cys) from homocysteine (Hcy) and glutathione (GSH).
Xuan Zhang, Xuan Zhang, Li Zhang, Wei-Wei Ma, Yong Zhou, Zhen-Ni Lu, Suying Xu   +6 more
doaj   +1 more source

Protective Roles of Hydrogen Sulfide in Alzheimer’s Disease and Traumatic Brain Injury

Antioxidants, 2023
The gaseous signaling molecule hydrogen sulfide (H2S) critically modulates a plethora of physiological processes across evolutionary boundaries. These include responses to stress and other neuromodulatory effects that are typically dysregulated in aging,
Bindu D. Paul, Andrew A. Pieper
doaj   +1 more source