Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Normal Values for Respiratory Oscillometry in Pediatrics: An Argument for a Local Control Population. [PDF]
Boas H +8 more
europepmc +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Enhanced lung volumes and pressures in traditional wind instrument musicians: The case of the Mejwez. [PDF]
Darabseh MZ +7 more
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The correlation of umbilical cord blood quality and placental function with neonatal outcomes in fetal growth restriction. [PDF]
Zou L +5 more
europepmc +1 more source
[Retracted] Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine‑γ‑lyase function. [PDF]
Chen L, Li X, Liu L, Yu B, Xue Y, Liu Y.
europepmc +1 more source
A grave complication: propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis. [PDF]
Christopoulos C +3 more
europepmc +1 more source
A Tutorial on Optimal Dynamic Treatment Regimes. [PDF]
Wang C, Tom BDM.
europepmc +1 more source
Keratin-5-positive basal-like epithelial cells associate with forced vital capacity in idiopathic pulmonary fibrosis; a cross-sectional analysis. [PDF]
Hirano T +5 more
europepmc +1 more source

