Results 201 to 210 of about 723,509 (268)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Exploiting the ability of Bacillus subtilis to synthetize surfactin under oxygen limitation. [PDF]

Appl Microbiol Biotechnol
Hiller E, Tadele LR, Miceta N, Notz D, Benatto Perino EH, Hausmann R.   +5 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Regulation of local chemistry in O3-type layered oxide cathodes for practical sodium-ion batteries. [PDF]

Chem Sci
Huo T, Yang Q, Yu G, Li M, Bai X, Lv T, Zhang X, Xu J, Liu K, Zhou X, Tan X, Li L, Lei K, Zheng S.   +13 more
europepmc   +1 more source

Morphological changes in smectic liquid crystal microstructures.

Soft Matter
Sato D, Sumino Y, Yamamoto T, Muševič I, Takenaka Y.   +4 more
europepmc   +1 more source

Formation of 5-methyl-2-furanmethanol which is a caramel flavor compound in the glutamic acid-glucose Maillard reaction: A ReaxFF-DFT study. [PDF]

Curr Res Food Sci
Pan X, Wei CK, Wang WL, Weng YN, Zheng AR, Sun LQ, Yang CM, Liu Y.   +7 more
europepmc   +1 more source

Fast Responses in L/H Transition

Fast Responses in L/H Transition
openaire  

Soft mode origin of charge ordering in superconducting kagome CsV₃Sb₅. [PDF]

Nat Commun
McGuinness PH, Henssler F, Alkorta M, Graf von Westarp MJ, Korshunov A, Bosak A, Ishikawa D, Baron AQR, Merz M, Haghighirad AA, Vergniory MG, Souliou SM, Heid R, Errea I, Le Tacon M.   +14 more
europepmc   +1 more source

Revisiting Stereocontrol through Ligand-Directed Non-Covalent Interactions in the Asymmetric Synthesis of Tetrahydrofuran Cores via Tsuji-Trost Asymmetric Allylic Alkylation. [PDF]

ACS Omega
Casali E, Toma L, Porta A, Zanoni G.
europepmc   +1 more source

Field-free control of magnetism and electronic states in ZGNR/h-BN heterojunctions <i>via</i> topological line defects. [PDF]

RSC Adv
Shan G, Chen W, Liu W.
europepmc   +1 more source