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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source

Independent living transitions for young people with cerebral palsy in Australia: aligning policy and practice with family realities. [PDF]

Front Public Health
Hickey L +7 more
europepmc +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source

RETRACTION: Fatty Acid Synthase Contributes to Epithelial-Mesenchymal Transition and Invasion of Salivary Adenoid Cystic Carcinoma Through PRRX1/Wnt/β-Catenin Pathway. [PDF]

J Cell Mol Med
europepmc +1 more source

Solvent-temperature coupled hydride transfer controls product selectivity in the HSiR3/KO t Bu catalytic system. [PDF]

Chem Sci
Yao H, Zhou Z, Liu Y, Zhang DH, Li G.
europepmc +1 more source

Morphological changes in smectic liquid crystal microstructures.