Results 241 to 250 of about 24,681,778 (305)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Spontaneous Curvature Sculpts Filament-Vesicle Morphogenesis. [PDF]

Nano Lett
Fang Y, Zhang C, Wang M, Shi C, Yi X.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The L-H Transition in Low Density Regimes

, 2000
Igitkhanov, Y., Pogutse, O., Connor, J., Janeschitz, G., Fielding, S., Sartori, R., Righi, E.   +6 more
openaire   +1 more source

Sequential changes in urinary crystal morphology in ethylene glycol poisoning: first human LV-SEM characterization of recovery-phase crystals. [PDF]

CEN Case Rep
Ito H, Hirose T, Suzuki Y, Yano K, Ishikawa R, Yuki T, Hashimoto H, Anan G, Shimada T, Itagaki H, Abe Y, Endo T, Mori T.   +12 more
europepmc   +1 more source

Conformation-Determined Segmental Dynamics in α-Poly-l-Lysine Hydrobromide: The Impact of Thermally Induced β-Sheet Formation on the Glass Transition Temperature. [PDF]

J Phys Chem B
Bielas R, Krishna Sudhakaran Nair Valsala Kumari A, Witkowicz K, Mielańczyk A, Tarnacka M, Janowska A, Jurkiewicz K, Kamiński K, Hachuła B, Kamińska E.   +9 more
europepmc   +1 more source

Luminescence Enhancement of an Indium(III) Complex Through Introducing an Electron-Donating Group in (1<i>H</i>-Pyrazol-1-yl)pyridazine. [PDF]

Molecules
Sedykh ES, Naletov NV, Komlyagina VI, Spiridonova YS, Musina EI, Rakhmanova MI, Romashev NF, Vinogradova KA, Nafikov MD, Vorob'ev AY, Fomenko IS, Gushchin AL.   +11 more
europepmc   +1 more source

Targeting super elongation complex-driven RNA polymerase II elongation reduces plaque vulnerability. [PDF]

Signal Transduct Target Ther
Kokot KE, Reichardt S, Menedo C, Erbe S, Kneuer JM, Palm KCA, Hoba J, Andritschke M, Katzmann M, Reuser A, von Scheidt M, Mokry M, Xiao J, Sheikh BN, Klöting N, Laufs U, Boeckel JN.   +16 more
europepmc   +1 more source