Results 101 to 110 of about 1,110,668 (287)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

2D Gravity and Random Matrices

, 1994
We review recent progress in 2D gravity coupled to ...
't Hooft, Alvarez-Gaumé, Ambjørn, Aoki, Bachas, Bachas, Banks, Belavin, Bershadsky, Bershadsky, Bershadsky, Bessis, Boulatov, Boulatov, Boulatov, Boutroux, Brezin, Brezin, Brézin, Brézin, Brézin, Brézin, Brézin, Crnković, D'Hoker, David, David, David, David, David, David, David, Di Francesco, Di Francesco, Di Francesco, Dijkgraaf, Dijkgraaf, Dijkgraaf, Dijkgraaf, Dijkgraaf, Distler, Dotsenko, Douglas, Douglas, Douglas, Douglas, Drinfeld, Eguchi, Eynard, Eynard, Feigin, Francesco, Francesco, Francesco, Francesco, Fröhlich, Fukazawa, Fukuma, Gaudin, Gerasimov, Ginsparg, Ginsparg, Ginsparg, Ginsparg, Ginsparg, Ginsparg, Goulian, Gross, Gross, Gross, Harish, Harris, Hille, Itzykson, Itzykson, J. Zinn-Justin, Karliner, Karliner, Kazakov, Kazakov, Kazakov, Kazakov, Kharchev, Klebanov, Knizhnik, Kontsevich, Kontsevich, Kostov, Kostov, Kostov, Kreuzer, Kunitomo, Kutasov, Kutasov, Li, Makeenko, Marinari, Marshakov, Marshakov, Martinec, Moore, Moore, P. Ginsparg, P.Di Francesco, Polyakov, Polyakov, Sakai, Seiberg, Seiberg, Selberg, Shenker, Staudacher, Tada, Weingarten, Witten, Witten, Witten, Zamolodchikov, Zinn-Justin   +118 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Radial variation of heat transport in L-mode JET discharges

Nuclear Fusion, 2019
In this paper, we analyze heat transport in the JET tokamak using data from its high resolution ECE diagnostic and analyses based on the transfer entropy (TE). The analysis reveals that heat transport is not smooth and continuous, but is characterized by 'trapping regions' separated by 'minor transport barriers'. Heat may 'jump over' these barriers and
van Milligen B Ph, Carreras A, de la Luna E, Solano E R, Abduallev S, Abhangi M, Abreu P, Afzal M, Aggarwal K M, Ahlgren T, Ahn J H, AhoMantila L, Aiba N, Airila M, Albanese R, Aldred V, Alegre D, Alessi E, Aleynikov P, Alfier A, Alkseev A, Allinson M, Alper B, Alves E, Ambrosino G, Ambrosino R, Amicucci L, Amosov V, Sunden E Andersson, Angelone M, Anghel M, Angioni C, Appel L, Appelbee C, Arena P, Ariola M, Arnichand H, Arshad S, Ash A, Ashikawa N, Aslanyan V, Asunta O, Auriemma F, Austin Y, Avotina L, Axton M D, Ayres C, Bacharis M, Baciero A, Baiao D, Bailey S, Baker A, Balboa I, Balden M, Balshaw N, Bament R, Banks J W, Baranov Y F, Barnard M A, Barnes D, Barnes M, Barnsley R, Wiechec A Baron, Orte L Barrera, Baruzzo M, Basiuk V, Bassan M, Bastow R, Batista A, Batistoni P, Baughan R, Bauvir B, Baylor L, Bazylev B, Beal J, Beaumont P S, Beckers M, Beckett B, Becoulet A, Bekris N, Beldishevski M, Bell K, Belli F, Bellinger M, Belonohy E, Ben Ayed N, Benterman N A, Bergsaker H, Bernardo J, Bernert M, Berry M, Bertalot L, Besliu C, Beurskens M, Bieg B, Bielecki J, Biewer T, Bigi M, Bilkova P, Binda F, Bisoffi A, Bizarro J P S, Bjorkas C, Blackburn J, Blackman K, Blackman T R, Blanchard P, Blatchford P, Bobkov V, Boboc A, Bodnar G, Bogar O, Bolshakova I, Bolzonella T, Bonanomi N, Bonelli F, Boom J, Booth J, Borba D, Borodin D, Borodkina I, Botrugno A, Bottereau C, Boulting P, Bourdelle C, Bowden M, Bower C, Bowman C, Boyce T, Boyd C, Boyer H J, Bradshaw J M A, Braic V, Bravanec R, Breizman B, Bremond S, Brennan P D, Breton S, Brett A, Brezinsek S, Bright M D J, Brix M, Broeckx W, Brombin M, Broslawski A, Brown D P D, Brown M, Bruno E, Bucalossi J, Buch J, Buchanan J, Buckley M A, Budny R, Bufferand H, Bulman M, Bulmer N, Bunting P, Buratti P, Burckhart A, Buscarino A, Busse A, Butler N K, Bykov I, Byrne J, Cahyna P, Calabro G, Calvo I, Camenen Y, Camp P, Campling D C, Cane J, Cannas B, Capel A J, Card P J, Cardinali A, Carman P, Carr M, Carralero D, Carraro L, Carvalho B B, Carvalho I, Carvalho P, Casson F J, Castaldo C, Catarino N, Caumont J, Causa F, Cavazzana R, CaveAyland K, Cavinato M, Cecconello M, Ceccuzzi S, Cecil E, Cenedese A, Cesario R, Challis C D, Chandler M, Chandra D, Chang C S, Chankin A, Coda S, Enachescu M, Fanni A, Fresa R, Gervasini G, Innocente P, Jardin A, Kos B, Laguardia L, Loarte A, Lukin A, Makwana R, Marchetto C, Matejcik S, Murari A, Muraro A, Naulin V, Paccagnella R, Pasqualotto R, Plyusnin V, Pomaro N, Puiatti M E, Refy D, Romanelli F, Sauter O, Soare S, Sozzi C, Subba F, Tardocchi M, Terranova D, Tokitani M, Uccello A, Vianello N, Vicente J, Wischmeier M   +234 more
openaire   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Conformational Analyses of Physiological Binary and Ternary Copper(II) Complexes with l‐Asparagine and l‐Histidine; Study of Tridentate Binding of Copper(II) in Aqueous Solution

ChemistryOpen, 2019
This study explores the structural properties and energy landscapes of the physiologically important bis(l‐asparaginato)copper(II) [Cu(l‐Asn)2] and (l‐histidinato)(l‐asparaginato)copper(II) [Cu(l‐His)(l‐Asn)]. The conformational analyses in the gas phase
Prof. Michael Ramek, Dr. Marijana Marković, Ilina Mutapčić, Jelena Pejić, Prof. Anne‐Marie Kelterer, Dr. Jasmina Sabolović   +5 more
doaj   +1 more source

L-mode-edge negative triangularity tokamak reactor [PDF]

Nuclear Fusion, 2019
M. Kikuchi, T. Takizuka, S. Medvedev, T. Ando, D. Chen, J.X. Li, M. Austin, O. Sauter, L. Villard, A. Merle, M. Fontana, Y. Kishimoto, K. Imadera   +12 more
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Self-Sustained Turbulence and L-Mode Confinement in Toroidal Plasmas [PDF]

Self-Sustained Turbulence and L-Mode Confinement in Toroidal Plasmas
A. Fukuyama, K. Itoh, M. Yagi, S.-I. Itoh   +3 more
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source