Results 281 to 290 of about 1,103,850 (332)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Development and Validation of a Nomogram Model for Predicting Chorioamnionitis in Patients with Term Premature Rupture of Membranes. [PDF]

Int J Womens Health
Gao H, Gong L, Li Y, Huang W, Zhao J, Ren Z, Huang X, Lu J.   +7 more
europepmc   +1 more source

Electron heat transport dependence on plasma shape and collisionality in EC heated L-mode TCV plasmas

, 2005
Y. Camenen, A. Pochelon, A. Bottino, I. Pavlov, R. Behn, S. Coda, T. Goodman, Henderson, J.-M. Moret, L. Porte, O. Sauter, G. Zhuang   +11 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Analytical study of mode filtering in a duct with resistive layers. [PDF]

PLoS One
Alahmadi H, Afzal M, Javeed U, Nawaz T.
europepmc   +1 more source

Identifying Key Metabolites in South African Medicinal Plants Using Dual Electrospray Ionization Metabolomics. [PDF]

Plants (Basel)
Makhafola MA, Naidoo CM, Obi CL, Iweriedor BC, Olaokun OO, Prinsloo E, Zubair MS, Mkolo NM.   +7 more
europepmc   +1 more source

SOL power decay length correlations with electron pressure pedestal top and pedestal gradients across L, I and H-modes at ASDEX Upgrade

, 2019
D. Silvagni, T. Eich, M. Faitsch, T. Happel, B. Sieglin, P. David, D. Nille, Linda Gil, U. Stroth, EUROfusion Mst Team   +9 more
openalex   +1 more source

Survey of tungsten gross erosion from main plasma facing components in WEST during a L-mode high fluence campaign

N. Fedorczak, C. Arnas, Luca Cappelli, L. Colas, Y. Corre, M. Diez, A. Gallo, J. Gaspar, A. Grosjean, C. Guillemaut, J. Gunn, C. A. Johnson, C. Martin, E. Tsitrone, E.A. Unterberg, J. Bucalossi   +15 more
openalex   +1 more source

Transcriptomic and metabolomic profiling reveals media- and host-dependent responses to <i>Staphylococcus hominis</i> in cell models. [PDF]

PeerJ
Liu W, Zhang T, Wang Q, Li Z, Bai Y, Xiao H, Wang Y, Xiao R, Tong L, Li Y, Qu X, Zhao X, Zhang Z, Sun H.   +13 more
europepmc   +1 more source